Scientific EditionDialkylaminoethyl Esters of 4-Nitro- and 4-Amino- 3 -hydroxy-2 -naphthoic Acids**

Add time:09/08/2019    Source:sciencedirect.com

The 2-diethylaminoethyl ester of 3-hydroxy-2-naphthoic acid was nitrated in acetic acid solution to yield the corresponding ring-substituted 4-nitro derivative. Catalytic hydrogenation of the nitro compound gave 2-diethylaminoethyl 4-amino-3-hydroxy-2-naphthoate hydrochloride. The anesthetic properties of these nitro and amino derivatives have been studied and compared with unsubstituted 3-hydroxy-2-naphthoic acid esters of the same series.

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