Original articleA new model of detrusor overactivity in conscious rats induced by Retinyl acetate (cas 127-47-9) instillation
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Add time:09/10/2019 Source:sciencedirect.com
IntroductionA credible animal overactive bladder model used in basic research is an indispensable harbinger of safe and ethical clinical trials on human subjects. Our objective was to develop a new animal model of a hyperactive bladder that will be void of inflammatory urothelium lesions and display significant sensitivity to muscarinic receptor antagonists.
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