Derivatives of 1-fluoroaziridine-2,2-dicarboxylic acid

Add time:09/10/2019    Source:sciencedirect.com

Derivatives of 1-fluoroaziridine-2,2-dicarboxylic acid 10−14 have been synthesized for the first time and characterized by spectroscopic methods; nucleophilic reactions of dimethyl 1-fluoroaziridine-2,2-dicarboxylate, such as transesterification and amidation, occur predominantly at the carboxy group trans-oriented with respect to the N-substituent.

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