Reverse-benzamidine antimalarial agents: Design, synthesis, and biological evaluation
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Add time:09/24/2019 Source:sciencedirect.com
In the frame of the development of bis-cationic choline analogs, the RSA of bis-N-alkylamidines were studied and a new series of reverse-benzamidine derivatives was designed. Contrary to the lipophilicity, the basicity of alkylamidine compounds directly influences their antimalarial potencies.
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