NoteSynthesis and glycosylation of pyrimidin-2-yl 1-thio-α-d-manno- and -α-l-rhamnopyranoside

Add time:09/30/2019    Source:sciencedirect.com

Pyrimidin-2-yl 2,3,4,6-tetra-O-benzyl-1-thio-α-d-mannopyrano side (9), pyrimidin-2-yl 2,3,4-tri-O-benzyl-α-l-rhamnopyranoside (10), pyrimidin-2-yl 2-O-acetyl-3,4,6-tri-O-benzyl-1-thio-α-d-mannopyranoside (7), and pyrimidin-2-yl 2-O-acetyl-3,4-di-O-benzyl-1-thio-α-l-rhamnopyranoside (8) were prepared almost quantitatively from the corresponding protected 1,2-O-methoxyethylidene-β-d-manno-or-β-l-rhamnopyranose with 2-mercaptopyrimidine in the presence of mercuric bromide. Coupling reactions of the thioglycosides promoted by silver triflate with suitable glycosyl acceptors afforded 1,2-trans linked disaccharides.

We also recommend Trading Suppliers and Manufacturers of METHYL ALPHA-L-RHAMNOPYRANOSIDE (cas 15814-59-2). Pls Click Website Link as below: cas 15814-59-2 suppliers

Prev:Lewis-acid-catalysed isomerisation of benzylidene acetals of methyl α-l-rhamnopyranoside and methyl β-l-arabinopyranoside derivatives
Next:Polymer paperStationary fluorescence depolarization study of mobility of rigid probes in bulk elastomers: Motion of dimethylanthracene and three trans-diphenylpolyenes inserted in polyisoprene, polybutadiene and random butadiene-styrene copolymers)