Domino cyclocondensation of arylaldehydes with 2-Acetylpyridine (cas 1122-62-9)
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Add time:09/25/2019 Source:sciencedirect.com
A novel synthetic route for the preparation of cyclohexane skeleton 3 was developed via the one-pot domino Claisen–Schmidt condensation reaction/Michael addition/double aldol reaction of 1 equiv of functionalized arylaldehyde 1 with 3 equiv of 2-acetylpyridine (2a).
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