Palladium-catalyzed conjugate addition of arylboronic acids to 2-substituted chromones in aqueous media
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Add time:09/27/2019 Source:sciencedirect.com
Palladium-catalyzed conjugate additions of arylboronic acids to 2-alkylchromones are reported. The conjugate additions occur in aqueous media in the presence of a catalyst generated from palladium trifluoroacetate and 1,10-phenanthroline, and the flavanone derivatives containing a fully-substituted carbon center are formed in up to 90% yield.
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