An efficient synthesis of the opioid analgesic (R)-phenampromide (cas 129-83-9) via an aziridinium ion

Add time:09/25/2019    Source:infona.pl

A simple and efficient synthesis of the opioid analgesic agent (R)-phenampromide with high enantiopurity (>99% ee) via the formation of an aziridinium ion as a key step using commercially available starting material is described.

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