A new method for the preparation of (2R)-2-amino-5-phosphonopentanoic acid.

Add time:07/15/2019    Source:sciencedirect.com

A new and efficient synthesis of (2R)-2-amino-5-phosphonopentanoic acid(AP5) is reported. Our approach is based on a pseudo-Claisen [2,3] sigmatropic rearrangement of an alkyne phosphite.

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