Synthesis of [3α‐3H] 17α‐Hydroxy Pregnenolone (cas 145-13-1) and [3α‐3H] Pregnenolone (cas 145-13-1)
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Add time:09/29/2019 Source:infona.pl
For the first time, [3α‐3H] 17α‐hydroxy Pregnenolone (cas 145-13-1) (1) was synthesized through a multiple step sequence. The presence of [3β‐3H] isomer in RP‐HPLC purified product was identified by tritium NMR. The [3β‐3H] isomer was then separated from [3α‐3H] 17α‐hydroxy pregnenolone with chiralPAK AD‐H column. [3α‐3H] pregnenolone (2) was synthesized from commercial available 5‐pregnen‐3,20‐dione in one step with an improved procedure.
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Next:Ectopic expression of MHC class II genes (RT1.B(I) β/α) in rat hepatocytes in vivo and in culture can be elicited by treatment with the pregnane X receptor agonists Pregnenolone (cas 145-13-1) 16α-carbonitrile and dexamethasone) - 【Back】【Close 】【Print】【Add to favorite 】
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- Ectopic expression of MHC class II genes (RT1.B(I) β/α) in rat hepatocytes in vivo and in culture can be elicited by treatment with the pregnane X receptor agonists Pregnenolone (cas 145-13-1) 16α-carbonitrile and dexamethasone09/30/2019
- Patients with premenstrual syndrome have decreased saccadic eye velocity compared to control subjects - Study on serum Pregnenolone (cas 145-13-1), Pregnenolone (cas 145-13-1) sulfate, 5α-pregnan-3,20-dione and 3α-hydroxy-5α-pregnan-20-one09/28/2019