Special features of the nucleophilic substitution of halogen in alkyl and benzyl halides with anions generated from 4-Hydroxy-2-mercapto-6-methylpyrimidine (cas 195-64-2)
-
Add time:09/28/2019 Source:infona.pl
The nucleophilic substitution of halogen (chlorine, bromine, and iodine) in alkyl and benzyl halides has been effected in aqueous dioxane media with S-and O-anions generated from 4-hydroxy-2-mercapto-6-methylpyrimidine. Under these conditions replacement of halogen proceeds by an SN2 mechanism and the reactivity of S-anions is 10 times greater than that of O-anions, which is in agreement with the results of ab initio quantum-chemical calculations of the electronic structure and total energy of transition states, carried out within the framework of the restricted Hartree-Fock method, basis 6-31G**.
We also recommend Trading Suppliers and Manufacturers of 4-Hydroxy-2-mercapto-6-methylpyrimidine (cas 195-64-2). Pls Click Website Link as below: cas 195-64-2 suppliers
Prev:Conjugation of anti-dihydrodiol epoxides of benzo[a]pyrene, chrysene, benzo[c]phenanthrene and dibenz[a,h]anthracene with glutathione catalyzed by cytosol and by the Mu-class glutathione transferase HTP II from rat liver
Next:Solvothermal synthesis and structural characterization of a novel one-dimensional organotin polymer involving high centrosymmetric units containing polyfunctional ligand 4-Hydroxy-2-mercapto-6-methylpyrimidine (cas 195-64-2)) - 【Back】【Close 】【Print】【Add to favorite 】