A new enantioselective synthesis of (4S, 5S)-5-(N-Boc)-amino-6-cyclohexyl-4-hydroxy-hexanoic acid lactone, a hydroxyethylene dipeptide isostere precursor

Add time:07/18/2019    Source:sciencedirect.com

A new enantioselective synthesis of a valuable hydroxyethylene dipeptide isostere precursor, (4S, 5S)-5-5(N-Boc)-amino-6-cyclohexyl-4-hydroxy-hexanoic acid lactone, has been developed by using coupling reaction of chiral triflates as a key step.

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