Biooxidation of 7,12-dimethylbenz[a]anthracene in rat subcutaneous tissue
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Add time:07/17/2019 Source:sciencedirect.com
The present study demonstrates the biooxidation of 7,12-dimethylbenz[a]anthracene to the corresponding hydroxyalkyi metabolites, 7-hydroxymethylbenz[a]anthracene, 7-hydroxymethyl-12-methylbenz[a] anthracene, and 7,12-dihydroxymethylbenz[a]anthracene in the dorsal subcutaneous tissue of the rat, in vivo, a tissue highly susceptible to the carcinogenic action of 7,12-dimethylbenz[a] anthracene.
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