Hydroxymethylation of the benzene ring

Add time:07/21/2019    Source:sciencedirect.com

The formation of 6-hydroxymethylbenzo(α)pyrene from benzo(α)pyrene has been shown to be catalyzed by sonicates of rat liver microsomes. The biosynthetic pathway for the formation of the aryl hydroxymethyl groups appears to be a direct hydroxymethylation of the benzene ring and not involve 6-methylbenzo(α)pyrene as an intermediate, because the formation of 6-hydroxymethylbenzo(α)pyrene is not a cytochrome P-450-mediated reaction, whereas a model aryl side chain methyl group hydroxylation has been shown to be inhibited by cytochrome P-450 inhibitors.

We also recommend Trading Suppliers and Manufacturers of 6-FORMYLBENZO(A)PYRENE (cas 13312-42-0). Pls Click Website Link as below: cas 13312-42-0 suppliers

Prev:Binding of 6-hydroxymethylbenzo[a]pyrene and 6-ace-toxymethylbenzo[a]pyrene to DNA
Next:Tetrakis(octadecylthio)Tetrathiafulvalene: Influence of Long Alkyl Chains on the Architecture and Electrochemical Properties of LB Films)