Synthesis of dibenzo[b,g][1,5]diazoninedione and isoindolo[2,1-a]quinazoline derivatives
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Add time:07/17/2019 Source:sciencedirect.com
Starting from 2-aminobenzonitrile 1 and 2-chloromethylbenzoyl chloride 2, a new synthetic pathway to tetracyclic compound 6 is described. Reaction of 2-aminobenzamide 7 with compound 2 leads to the tricyclic ring system 9 which was easily converted to compound 6 in the presence of KOH in refluxing H2O–EtOH.
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