Iodine-catalyzed synthesis of 5-benzoyl-8H-phthalazino[1,2-b]quinazolin-8-one derivatives via a domino reaction involving a benzyl automatic oxidation by oxygen

Add time:07/17/2019    Source:sciencedirect.com

A one-pot procedure for the synthesis of 5-benzoyl-8H-phthalazino[1,2-b]quinazolin-8-ones is achieved by an iodine-catalyzed reaction of 2-aminobenzohydrazides and 2-alkynylbenzaldehydes in good yields. The salient feature of this strategy is a domino type process including a condensation, addition, hydroamination, and a noteworthy benzyl automatic oxidation by oxygen under metal-catalyst-free conditions.

We also recommend Trading Suppliers and Manufacturers of 8-BENZYL (S)-2-AMINOOCTANEDIOATE (cas 116052-00-7). Pls Click Website Link as below: cas 116052-00-7 suppliers

Prev:Antimicrobial and toxic effect in vitro of a bisdequalinium (cas 16776-40-2) acetate solution for endodontic use
Next:Novel 8-(p-substituted-phenyl/benzyl)xanthines with selectivity for the A2A adenosine receptor possess bronchospasmolytic activity)