Monitoring the solid phase synthesis of analogues of lysobactin and the katanosins using in situ MALDI-TOF MS

Add time:07/17/2019    Source:sciencedirect.com

A method of solid phase reaction analysis is described using an in situ cleavage process (TFA vapour) followed by MALDI-TOF MS analysis. The process is demonstrated by the solid phase synthesis of a depsipeptide based on the antibiotic Lysobactin.

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