The Use of Hydrogenated Cottonseed Oil and hexadienol (cas 11131-15-0) as Suppository Bases

Add time:07/19/2019    Source:sciencedirect.com

Suppository bases were formulated from mixtures of hydrogenated cottonseed oil and hexadienol (cas 11131-15-0) with various other ingredients. Suppositories were prepared from these bases that were satisfactory with respect to appearance and consistency. The potential of the bases to release a medicament was determined by a colorimetric method. The effect of Veegum® and other agents on the release of medicament from the base is reported. Suppositories made from these bases were stored for one year and the results of storage are reported. A more detailed study of these bases using other emulsifying agents is recommended.

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