The metabolism of metronidazole (1 -2′-hydroxyethyl-2-methyl-5-nitroimidazole)

Add time:07/18/2019    Source:sciencedirect.com

The metabolism of metronidazole has been studied in man and dog, and was similar in both species. The urine contained unchanged metronidazole (I), the corresponding acid, 2-methyl-5-nitroimidazole-1-ylacetic acid (II), and a second metabolite which has been tentatively identified as the ether glucuronide of metronidazole (III).

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