Gemfibrozil (25812-30-0),Gemfibrozil (25812-30-0) Manufacturers & Suppliers,Synthesis,MSDS

Basic information

Name:
Gemfibrozil
CAS No.:
25812-30-0
Molecular Structure:
Formula:
C₁₅H₂₂O₃
Molecular Weight:
250.37
Synonyms:
2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure;Lipira;Normolip;2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid;Valeric acid, 2,2-dimethyl-5-(2,5-xylyloxy)-;WL-Gemfibrozil;Gozid;Litarek;Gemfibrozilum [INN-Latin];Pentanoic acid,5-(2,5-dimethylphenoxy)-2,2- dimethyl-;Apo-Gemfibrozil;Lipazil;Regulip;Lanaterom;Gemfibromax;Low-Lip;Gevilon Uno;Gemfibrozil [USAN:BAN:INN];Decrelip;Taborcil;Micolip;CI 719;Lifibron;Sinelip;Ipolipid;Reducel;2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaeure;Gemfibrozil (JAN/USP);CI-719;Fibratol;Jezil;Brozil;Gemfibrozilo [INN-Spanish];Hipolixan;Gemd;Pilder;Gem-S;Lipur;5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid;Fibrocit;Lopid;Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-;Ausgem;Gemnpid;Clearol;
EINECS:
247-280-2
Density:
1.044 g/cm³
Melting Point:
61-63 °C
Boiling Point:
394.7 °C at 760 mmHg
Flash Point:
141.6 °C
Appearance:
White crystalline powder
Hazard Symbols:
Xn, Xi
Risk Codes:
22-63-62-46-36/38-21
Safety Description:
36-53-36/37-26-25 Details

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Chemistry

Molecular Formula: C₁₅H₂₂O₃
Molecular Weight: 250.33
EINECS: 247-280-2
Melting point: 61-63 °C
Index of Refraction: 1.511
Density: 1.044 g/cm³
Flash Point: 141.6 °C
Enthalpy of Vaporization: 68 kJ/mol
Boiling Point: 394.7 °C at 760 mmHg
Vapour Pressure: 6.13E-07 mmHg at 25 °C
Appearance: White crystalline powder
Structure of Gemfibrozil (CAS NO.25812-30-0):

IUPAC Name: 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
Product Category of Gemfibrozil (CAS NO.25812-30-0): Active Pharmaceutical Ingredients;APIs;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Intracellular receptor

Uses

Gemfibrozil (CAS NO.25812-30-0) is a serum lipid regulating agent used as an antihyperlipoproteinemic.

Toxicity Data With Reference

1.		orl-rat LD50:4786 mg/kg		PRSMA4 Proceedings of the Royal Society of Medicine. 69 (Suppl 2)(1976),15.
2.		orl-mus LD50:3162 mg/kg		PRSMA4 Proceedings of the Royal Society of Medicine. 69 (Suppl 2)(1976),15.

Safety Profile

Hazard Codes: Harmful Xn, Irritant Xi
Risk Statements: 22-63-62-46-36/38-21
R21:Harmful in contact with skin.
R22:Harmful if swallowed.
R36/38:Irritating to eyes and skin.
R46:May cause heritable genetic damage.
R62:Risk of impaired fertility.
R63:Possible risk of harm to the unborn child.
Safety Statements: 36-53-36/37-26-25
S25:Avoid contact with eyes.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S36/37:Wear suitable protective clothing and gloves.
S53:Avoid exposure - obtain special instructions before use.

Specification

Gemfibrozil , its cas register number is 25812-30-0. It also can be called 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid ; Lipur ; Decrelip ; Trialmin ; Litarek ; Bolutol ; Lipazil ; Ausgem ; Pilder ; and Lopid .