Ethanol,2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride(1:2)

The Hydroxyzine dihydrochloride is an organic compound with the formula C₂₁H₂₇ClN₂O₂^.2(HCl). The IUPAC name of this chemical is 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol dihydrochloride. With the CAS registry number 2192-20-3, it is also named as 2-(2-(4-(p-Chloro-α-phenylbenzyl)-1-piperazinyl)ethoxy)ethanol dihydrochloride. The product's categories are Intermediates & Fine Chemicals; Pharmaceuticals; InhibitorsMulti-Drug Resistance and Drug Metabolism; Cell Signaling Enzymes; Drug and Xenobiotic Metabolism; Substrates, Inducers, Inhibitors; Xenobiotics and Drug Metabolism. Besides, it is a white solid, which should be stored in a colsed place. It is H1 receptor antagonist. It is also used as anxiolytic and antihistaminic.

Physical properties about Hydroxyzine dihydrochloride are: (1)ACD/LogP: 2.03; (2)ACD/LogD (pH 5.5): 1.17; (3)ACD/LogD (pH 7.4): 2; (4)ACD/BCF (pH 5.5): 2.84; (5)ACD/BCF (pH 7.4): 18.99; (6)ACD/KOC (pH 5.5): 41.95; (7)ACD/KOC (pH 7.4): 280.22; (8)#H bond acceptors: 4; (9)#H bond donors: 1; (10)#Freely Rotating Bonds: 9; (11)Polar Surface Area: 24.94 Å²; (12)Flash Point: 255.7 °C; (13)Enthalpy of Vaporization: 80.82 kJ/mol; (14)Boiling Point: 499.2 °C at 760 mmHg; (15)Vapour Pressure: 8.78E-11 mmHg at 25°C.

Preparation: this chemical can be prepared by 1-[2-(2-hydroxyethoxy) ethyl piperazine and chloro diphenyl methyl chloride.

When you are using this chemical, please be cautious about it as the following:
It is harmful if swallowed. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, this chemical is irritating to eyes, respiratory system and skin.

You can still convert the following datas into molecular structure:
(1)SMILES: Cl.Cl.Clc1ccc(cc1)C(c2ccccc2)N3CCN(CC3)CCOCCO
(2)InChI: InChI=1/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
(3)InChIKey: ANOMHKZSQFYSBR-UHFFFAOYAD
(4)Std. InChI: InChI=1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
(5)Std. InChIKey: ANOMHKZSQFYSBR-UHFFFAOYSA-N

The toxicity data is as follows: