Basic information
- Name:
Rutin
- CAS No.:
153-18-4
- Molecular Structure:

- Formula:
- C27H30O16
- Synonyms:
- Forsythia fruit;Birutin;Oxyritin;4H-1-Benzopyran-4-one, 3-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-;Venoruton;Rutinion acid;Tanrutin;C.I. 75730;Rutinic acid;Rutoside;
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Chemistry
Structure of Rutin (CAS NO.153-18-4):

IUPAC Name: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
Empirical Formula: C27H30O16
Molecular Weight: 610.5175g/mol
EINECS: 205-814-1
Molar Volume: 334.1 cm3
Polarizability: 54.77×10-24cm3
Surface Tension: 125.2 dyne/cm
Density: 1.82 g/cm3
Flash Point: 325.4 °C
Enthalpy of Vaporization: 150.12 kJ/mol
Melting Point: 195 °C (dec.)(lit.)
Boiling Point: 983.1 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C
Solubility pyridine: 50 mg/mL
Water Solubility 12.5 g/100 mL
Product Categories: Flavanols;Biochemistry;Disaccharides;Flavonoids;Glycosides;Sugars;Natural Plant Extract;Intermediates & Fine Chemicals;Pharmaceuticals
Canonical SMILES: CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O
Isomeric SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O
InChI: InChI=1S/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-33,35-38H,7H2,1H3/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-/m0/s1
InChIKey: IKGXIBQEEMLURG-NVPNHPEKSA-N
Uses
Found of Rutin (CAS NO.153-18-4) in many plants, especially the buckwheat plant. Identity with ilixanthin. Capillary protectant
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | intraperitoneal | 2gm/kg (2000mg/kg) | Eksperimentalna Meditsina i Morfologiya. Vol. 19, Pg. 207, 1980. | |
| mouse | LD50 | intraperitoneal | 200mg/kg (200mg/kg) | National Technical Information Service. Vol. AD277-689, | |
| mouse | LD50 | intravenous | 950mg/kg (950mg/kg) | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 556, 1950. | |
| rat | LD50 | intraperitoneal | 2gm/kg (2000mg/kg) | Eksperimentalna Meditsina i Morfologiya. Vol. 19, Pg. 207, 1980. |
Safety Profile
Hazard Codes of Rutin (CAS NO.153-18-4):
Xn,
Xi
Risk Statements: 22-36/37/38
R22: Harmful if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26
S24/25: Avoid contact with skin and eyes.
S36: Wear suitable protective clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: VM2975000
F: 8
Specification
Rutin , its cas register number is 153-18-4. the other name is rutoside , quercetin-3-rutinoside and sophorin , is a citrus flavonoid glycoside found in buckwheat, the leaves and asparagus,and petioles of Rheum species, . Rutin is also found in the fruit of the Fava D'Anta tree ,fruits and fruit rinds and berries such as mulberry and cranberries. Its name comes from the name of Ruta graveolens, a plant that also contains rutin.
The Health effects information of Rutin (CAS NO.153-18-4):
1. It has anti-inflammatory activity.
2. It inhibits platelet aggregation, making the blood thinner and improves circulation.
3. It inhibits aldose reductase activity. Aldose reductase is an enzyme normally present in the eye and elsewhere in the body.
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