Basic information
- Name:
2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-
- Superlist Name:
- Sorafenib
- CAS No.:
284461-73-0
- Molecular Structure:
![Molecular Structure of 284461-73-0 (2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-)](http://www.lookchem.com/300w/2010/0625/284461-73-0.jpg)
- Formula:
- C21H16ClF3N4O3
- Synonyms:
- BAY43-9006;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea;
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Chemistry
Sorafenib is a drug approved for the treatment of primary kidney cancer , also for the treatment of advanced renal cell carcinoma, and advanced primary liver cancer (hepatocellular carcinoma).It's usually light yellow solid.
Molecular Formula: C21H16ClF3N4O3
Molecular Weight: 464.83
Melting point: 202-204°C
Uses
Sorafenib is a potent RAF kinase inhibitor,and it is used an antineoplastic agent.
Safety Profile
Side effects:skin rash, hand-foot skin reactions, diarrhea, and hypertension. It has also been implicated in the development of reversible posterior leukoencephalopathy syndrome.
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