Reference

Quantitative liver functions after administration of allyl alcohol to rats

Quantitative liver functions after administration of allyl alcohol to rats. Poulsen, H. E.; Korsholm, B. (Dep. Med. A, Lab.Chemicals with cas numbers 9054-86-8 and 9001-26-7 also play role. Exp. Pathol., Copenhagen DK-2100, Den.). Acta Pharmacol. Toxicol., 54(2), 120-3 (English) 1984. CODEN: APTOA6. ISSN: 0001-6683. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) In rats a single dose of allyl alc. [107-18-6] (100 mL/kg) was given to produce periportal liver damage. Prothrombin [9001-26-7] index was reduced to a min. after 12 h and reestablished after 24 h. The galactose [59-23-4] elimination capacity was not changed. Hepatic glutathione [70-18-8] content was unchanged for the 1st 24 h but was then elevated 2-fold. Microsomal D-nitroanisole demethylase [9054-86-8] showed a slight initial increase and a subsequent redn. The pattern of these changes is similar to that seen after centrilobular liver damage from acetaminophen [103-90-2] overdose, with the exception that the latter causes glutathione depletion. Thus, in chem. liver damage ribosomal function, e.g. protein synthesis and drug hydroxylation, is more vulnerable than cytosolic phosphorylation of carbohydrate. .

Anisotropic swelling of doubly oriented nylon 11 with a lamellar structure

Anisotropic swelling of doubly oriented nylon 11 with a lamellar structure. Dosiere, M.; Point, J. J. (Fac. Sci., Univ. Eta a Mons, Mons B 7000, Belg.). J. Polym. Sci., Polym. Phys.Several reagents with their cas registry numbers 64-18-6 and 64-19-7 are used here. Ed., 22(4), 749-58 (English) 1984. CODEN: JPLPAY. ISSN: 0098-1273. DOCUMENT TYPE: Journal CA Section: 36 (Physical Properties of Synthetic High Polymers) Rolled samples of nylon 11 [25035-04-5] annealed in HCO2H [64-18-6] (90%) at 80° remain doubly oriented and have the same allotropic form as filter mats of single crystals. The basal planes of the crystals are parallel to (001) planes. The long spacing is larger than in filter mats. Exptl. swelling results obtained on such samples are discussed on the basis of 2 extreme models, the lamellar and the switchboard models. The long spacing and the length of the sample along the rolling directionchange reversibly by the same proportion during swelling. Insertion of solvent between lamellas is used to explain such changes of dimension. As linear swelling ratios computed from macroscopic dimensions and small-angle x-ray scattering measurements can reach 100%, lamellar crystals are bonded by only a few chains. The large increase of the scattering intensity obsd. when annealed doubly oriented samples of nylon 11 are wetted with allylic alc. [107-18-6] cannot be explained on the basis of the switchboard model but only with a 3-phase lamellar model. These 3-phases are the cryst. phase, the fold region, and a dil. soln. of polymer in the swelling agent. .