Products Categories
| CAS No.: | 124473-12-7 |
|---|---|
| Name: | 2-CHLOROMETHYL-4-METHOXY-3-METHYLPYRIDINE HYDROCHLORIDE |
| Article Data: | 3 |
| Molecular Structure: | |
|
|
|
| Formula: | C8H10ClNO |
| Molecular Weight: | 171.626 |
| Synonyms: | Lafutidine Pibutidine intermediate |
| EINECS: | 1806241-263-5 |
| Density: | 1.139 g/cm3 |
| Boiling Point: | 257.508 °C at 760 mmHg |
| Flash Point: | 109.537 °C |
| Appearance: | Light yellow liquid |
| PSA: | 22.12000 |
| LogP: | 2.93940 |
- 144851-82-1METHYL2-AMINO-3-FLUOROBENZOATE
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 173606-50-3BOC-10-AMINODECANOIC ACID
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 86604-77-5
2-hydroxymethyl-4-methoxy-3-methylpyridine
- 124473-12-7
2-chloromethyl-3-methyl-4-methoxypyridine
| Conditions | Yield |
|---|---|
| With thionyl chloride In dichloromethane at 25℃; for 2h; | |
| With thionyl chloride In dichloromethane at 0℃; |
- 37699-43-7
2,3-dimethyl-4-nitropyridine N-oxide
- 124473-12-7
2-chloromethyl-3-methyl-4-methoxypyridine
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: 82 percent / K2CO3 / 20 h / Heating 2: 110 °C 3: 10percent aq. HCl / 1.5 h / 90 °C 4: SOCl2 / CH2Cl2 / 0 °C View Scheme |
- 102625-96-7
4-methoxy-2,3-dimethylpyridine 1-oxide
- 124473-12-7
2-chloromethyl-3-methyl-4-methoxypyridine
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: 110 °C 2: 10percent aq. HCl / 1.5 h / 90 °C 3: SOCl2 / CH2Cl2 / 0 °C View Scheme | |
| Multi-step reaction with 3 steps 1: AcOH / 120 °C 2: 2N aq. NaOH / methanol / 2 h / 25 °C 3: SOCl2 / CH2Cl2 / 2 h / 25 °C View Scheme |
- 102625-98-9
2-acetoxymethyl-4-methoxy-3-methylpyridine
- 124473-12-7
2-chloromethyl-3-methyl-4-methoxypyridine
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: 10percent aq. HCl / 1.5 h / 90 °C 2: SOCl2 / CH2Cl2 / 0 °C View Scheme | |
| Multi-step reaction with 2 steps 1: 2N aq. NaOH / methanol / 2 h / 25 °C 2: SOCl2 / CH2Cl2 / 2 h / 25 °C View Scheme |
- 90070-09-0
2-mercaptothieno<3,4-d>imidazole
- 124473-12-7
2-chloromethyl-3-methyl-4-methoxypyridine
- 111371-73-4
2-(4-Methoxy-3-methyl-pyridin-2-ylmethylsulfanyl)-1H-thieno[3,4-d]imidazole
| Conditions | Yield |
|---|---|
| In ethanol Heating; | 59% |
- 124473-12-7
2-chloromethyl-3-methyl-4-methoxypyridine
- 134469-07-1
Benzimidazol-2-thiol
- 102804-82-0
2-[[(4-methoxy-3-methylpyridin-2-yl)methyl]mercapto]-1H-benzimidazole
| Conditions | Yield |
|---|---|
| With sodium hydroxide In ethanol Heating; Yield given; |
- 124473-12-7
2-chloromethyl-3-methyl-4-methoxypyridine
- 111371-27-8
2-(4-methoxy-3-methyl-2-picolyl-sulfinyl)-1H-thieno[3,4-d]imidazole
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: 59 percent / ethanol / Heating 2: 65 percent / aq. sodium bicarbonate, m-chloroperbenzoic acid / CH2Cl2 / 0.17 h / 0 °C View Scheme |
- 81864-06-4
5,7-dihydro-2-mercapto-5,5,7,7-tetramethylindeno[5,6-d]-imidazol-6(1H)-one
- 124473-12-7
2-chloromethyl-3-methyl-4-methoxypyridine
- 101387-97-7
5,7-dihydro-2-[[(4-methoxy-3-methyl-pyridin-2-yl)methyl]thio]-5,5,7,7-tetramethylindeno[5,6-d]imidazol-6(1H)-one
| Conditions | Yield |
|---|---|
| In acetone |
- 20667-12-3Silver oxide
- 563-63-3Aceticacid, silver(1+) salt (1:1)
- 166663-25-8Echinocandin B,1-[(4R,5R)-4,5-dihydroxy-N2-[[4''-(pentyloxy)[1,1':4',1''-terphenyl]-4-yl]carbonyl]-L-ornithine]-
- 101-21-3Chlorpropham
- 189005-44-56-Methyl-2-(4-methylphenyl)imidazol[1,2-a]-pyridine-3-acetic acid
- 55-21-0Benzamide
- 71320-77-9Benzamide,4-chloro-N-[2-(4-morpholinyl)ethyl]-
- 477-73-6Phenazinium,3,7-diamino-2,8-dimethyl-5-phenyl-, chloride (1:1)
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
What can I do for you?
Get Best Price
Specification
The systematic name of this chemical is 2-(chloromethyl)-4-methoxy-3-methylpyridine. With the CAS registry number 124473-12-7, it is also named as pyridine, 2-(chloromethyl)-4-methoxy-3-methyl-. In addition, the formula is C8H10ClNO and the molecular weight is 171.59.
The other characteristics of this product can be summarized as: (1)ACD/LogP: 2.17; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2; (4)ACD/LogD (pH 7.4): 2; (5)ACD/BCF (pH 5.5): 8; (6)ACD/BCF (pH 7.4): 12; (7)ACD/KOC (pH 5.5): 129; (8)ACD/KOC (pH 7.4): 206; (9)#H bond acceptors: 2; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 22.12 Å2; (13)Index of Refraction: 1.518; (14)Molar Refractivity: 45.613 cm3; (15)Molar Volume: 150.63 cm3; (16)Polarizability: 18.082×10-24 cm3; (17)Surface Tension: 36.796 dyne/cm; (18)Density: 1.139 g/cm3; (19)Flash Point: 109.537 °C; (20)Enthalpy of Vaporization: 47.507 kJ/mol; (21)Boiling Point: 257.508 °C at 760 mmHg; (22)Vapour Pressure: 0.023 mmHg at 25°C.
Uses of 2-(Chloromethyl)-4-methoxy-3-methylpyridine: It can react with 3H-thieno[3,4-d]imidazole-2-thiol to get 2-(4-methoxy-3-methyl-pyridin-2-ylmethylsulfanyl)-3H-thieno[3,4-d]imidazole. This reaction needs solvent ethanol by heating. The yield is 59%.
![2-(Chloromethyl)-4-methoxy-3-methylpyridine can react with 3H-thieno[3,4-d]imidazole-2-thiol to get 2-(4-methoxy-3-methyl-pyridin-2-ylmethylsulfanyl)-3H-thieno[3,4-d]imidazole](/UserFilesUpload/Uses of 2-(Chloromethyl)-4-methoxy-3-methylpyridine.gif)
People can use the following data to convert to the molecule structure.
1. SMILES:ClCc1nccc(OC)c1C
2. InChI:InChI=1/C8H10ClNO/c1-6-7(5-9)10-4-3-8(6)11-2/h3-4H,5H2,1-2H3
3. InChIKey:UIRCDHHEYPUZGA-UHFFFAOYAJ