Reference

Reaction of glycosylidene diaziridines with acylating and sulfonylating agents

Reaction of glycosylidene diaziridines with acylating and sulfonylating agents. Mangholz, Sissi E. 126709-11-3 and 28920-43-6 are also occured in this study.; Briner, Karin; Bernet, Bruno; Vasella, Andrea ( Laboratorium fuer Organische Chemie, ETH-Hoenggerberg, Zurich CH-8093, Switz.). Helvetica Chimica Acta, 86(7), 2490-2508 (English) 2003 Verlag Helvetica Chimica Acta. CODEN: HCACAV. ISSN: 0018-019X. DOCUMENT TYPE: Journal CA Section: 33 (Carbohydrates) Acylation and sulfonylation of N,N'-unsubstituted glucosylidenespirodiaziridines with Ac2O, BzCl, FmocCl, TsCl, (naphthalen-2-yl)sulfonyl, and (2,4,6-triisopropylphenyl)sulfonyl chloride, and concomitant rearrangement gave the acylated and sulfonylated gluconolactone hydrazones in 40-83% yield. Similarly, the galacto and manno analogs and mannofuranosylidene-diaziridine were acetylated and tosylated. 15N-Labeling of D-gluco and D-galacto diaziridines showed that the pseudoequatorial NH of the gluco diaziridines and the pseudoaxial NH of the galacto diaziridines were preferentially acetylated and tosylated. Sulfonylation of the N-methylated diaziridines yielded the N-methyl-N-tosylglyconolactone hydrazones. The methylated N-atom of the diaziridines proved more reactive, irresp. of the configuration at C(2) and C(4). The products were readily hydrolyzed to glyconolactones. .

Applications of pre-column derivation for amino acids analysis

All Rights Reserved. Applications of pre-column derivation for amino acids analysis. Qu, Qishu; Tang, Xiaoqing; Hu, Xiaoya; Li, Shouchun (College of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, Peop. Rep. China). Huaxue Jinzhan, 18(6), 789-793 (Chinese) 2006 Huaxue Jinzhan Bianjibu.Several reagents with their cas registry numbers 605-65-2 and 28920-43-6 are used here. CODEN: HJINEL. ISSN: 1005-281X. DOCUMENT TYPE: Journal; General Review CA Section: 80 (Organic Analytical Chemistry) A review. Chromatog. sepn. combined with derivatization is widely used for anal. of amino acids. In this article, various representative reagents and corresponding derivatization processes were reviewed. The representative reagents include o-phthalaldehyde, dansyl-Cl, 2,4-dinitrofluorobenzene, phenylisothiocyanates, fluorescein isothiocyanates, chloroformates, and carbamates. .