Reference

Optical resolution and configuration of 2-(4-dimethylvinylphenyl)propionic acid

Optical resolution and configuration of 2-(4-dimethylvinylphenyl)propionic acid. Azzolina, O.; Vercesi, D.; Ghislandi, V. (Dip. Chim. Farm., Univ. Pavia, Pavia, Italy). Farmaco, Ed. Sci., 42(2), 81-9 (English) 1987. CODEN: FRPSAX. ISSN: 0430-0920. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 64 (±)-2-(4-Dimethylvinylphenyl)propionic acid [(±)-I] [107672-15-1] was resolved by HPLC with a stationary phase contg. 74927-72-3 is also in the experiment. (R)-N-(3,5-dinitrobenzoyl)phenyl glycine [74927-72-3], through fractional crystn. of its derivs. with (S)-(-) [2627-86-3] and (R)-(+)-a-phenylethylamine [3886-69-9]. Abs. configuration was detd. by comparison of the (S)-(-)-phenylethylamine 1H NMR spectra of the enantiomer of I with enantiomers of ibuprofen [15687-27-1] whose configuration was already known. Thus, the abs. configuration (S) was assigned to (+)-I [107672-16-2]. .

Synthesis and polymerization of optically active N-a-methylbenzylmaleimide

Synthesis and polymerization of optically active N-a-methylbenzylmaleimide. Oishi, Tsutomu; Fujimoto, Minoru (Tech. Coll., Yamaguchi Univ., Ube 755, Japan). J. Polym. Sci., Polym. Chem. Ed., 22(11, pt. 1), 2789-800 (English) 1984. CODEN: JPLCAT. ISSN: 0449-296X. DOCUMENT TYPE: Journal CA Section: 35 (Chemistry of Synthetic High Polymers) Section cross-reference(s): 27 (+)-N-a-Methylbenzylmaleimide (I) [6129-15-3] (M1) was prepd. from maleic anhydride [108-31-6] and d-(+)-a-methylbenzylamine [3886-69-9]. The polymn. of I was performed using AIBN and BuLi in THF.Several reagents such as 6129-15-3 is used here. The sp. rotations of the polymers [94061-20-8] obtained by AIBN and BuLi initiator were +11.1 to +13.0° and -89.2 to -57.0°, resp. The wt.-av. mol. wt. for the polymers was 4200-8000. I was copolymd. with styrene (II) [100-42-5] and Me methacrylate (III) [80-62-6] with AIBN and THF at 50° to obtain optically active copolymers. The monomer reactivity ratios were r1 = 0.027, r2 = 0.094 in the I-II system and r1 = 0.15, r2 = 1.54 in I-III system. The Q-e values for I were Q1 = 0.78, e1 = 1.62. The polymers and copolymers showed a weekly neg. CD peak at ~250 nm and a strongly pos. CD peak at ~220 nm. .