Reference

The introduction of oxygenated compounds in refining: impact and strategies

The introduction of oxygenated compounds in refining: impact and strategies. Valais, M.; Leprince, P. (Inst. Fr. Pet., Rueil-Malmaison 92506, Fr.). Rev. Inst. Fr. Pet., 39(6), 769-79 (French) 1984. CODEN: RFPTBH. ISSN: 0373-532X. DOCUMENT TYPE: Journal CA Section: 51 (Fossil Fuels, Derivatives, and Related Products) A computer-based tech.-economic evaluation was carried out of MeOH [67-56-1], EtOH [64-17-5], tert-BuOH [75-65-0], or MeOBu-tert [1634-04-4] addn. to gasoline (permissible 1984 level in France 5-10%) on the refining operations. All types of refineries were included in this evaluation.

Increased sensitivity to picrotoxin as an index of physical dependence on alcohol in the mouse

Increased sensitivity to picrotoxin as an index of physical dependence on alcohol in the mouse. Szabo, Gyula; Kovacs, Gabor L.; Telegdy, Gyula (Dep. Pathophysiol., Univ. Med. Sch., Szeged, Hung.). Drug Alcohol Depend., 14(2), 187-95 (English) 1984. CODEN: DADEDV. ISSN: 0376-8716. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) A relatively simple and rapid method was developed to induce tolerance to and dependence on EtOH [64-17-5] in mice. Alternating injections of metabolically stable tert-BuOH [75-65-0] and EtOH for 4 consecutive days resulted in a phys. dependence on Alc., which was quantified by the latency and medium ED (ED50) of picrotoxin [124-87-8]-induced central nervous system hyperexcitability-myoclonic and tonic seizures and mortality during the withdrawal period. Alc.-dependent animals in the withdrawal period seemed more susceptible than alc.-naive controls to picrotoxin. Withdrawal hyperexcitability can be quantitated by the ED50 of picrotoxin.