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(R)-Lactate

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Name

(R)-Lactate

EINECS 233-713-2
CAS No. 10326-41-7 Density 1.276 g/cm3
PSA 57.53000 LogP -0.54820
Solubility Soluble in water (50mg/ml) Melting Point 52.8°
Formula C3H6O3 Boiling Point 227.6 °C at 760 mmHg
Molecular Weight 90.0788 Flash Point 109.9 °C
Transport Information N/A Appearance N/A
Safety 26-39 Risk Codes 38-41
Molecular Structure Molecular Structure of 10326-41-7 ((R)-Lactate) Hazard Symbols IrritantXi
Synonyms

Lacticacid, D- (8CI);Propanoic acid, 2-hydroxy-, (R)-;(-)-Lactic acid;(2R)-2-Hydroxypropanoic acid;(R)-(-)-Lacticacid;(R)-2-Hydroxypropanoic acid;(R)-2-Hydroxypropionic acid;(R)-Lactic acid;(R)-a-Hydroxypropionic acid;D-(-)-Lactic acid;D-Lacticacid;

Article Data 179

(R)-Lactate Synthetic route

127-17-3

2-oxo-propionic acid

10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With phosphonic Acid; lactate dehydrogenase V152R mutant; phosphorous dehydrogenase I151R mutant; NAD In aq. buffer at 30℃; for 12h; pH=7.5; Reagent/catalyst; Time; Enzymatic reaction;100%
With phosphate buffer; ADH (EC 1.1.1.2); MV2+; nicotinamide adenine dinucleotide phosphate In water; tert-butyl alcohol for 30h; electrolysis' other reaction system;8.3E-6 mol
With Leuconostoc lactis ketoacid reductase; NADH In aq. phosphate buffer at 35℃; for 10h; pH=7; Enzymatic reaction; enantioselective reaction;65.2 %Chromat.
4254-14-2

(2R)-propane-1,2-diol

10326-41-7

D-Lactic acid

Conditions
ConditionsYield
Stage #1: (2R)-propane-1,2-diol With Rh(OTf)(trop2NH)(PPh3); water; cyclohexanone; sodium hydroxide at 20℃; for 5h; Inert atmosphere;
Stage #2: With hydrogenchloride In water Inert atmosphere; chemoselective reaction;
91%
232944-80-8

1-dodecyl L-lactate

A

10326-41-7

D-Lactic acid

B

112-53-8

1-dodecyl alcohol

Conditions
ConditionsYield
With 2C33H37N*H2O7S2; water at 80℃; for 4h;A 80%
B 87%
547-64-8

methyl lactate

A

10326-41-7

D-Lactic acid

B

27871-49-4

(S)-Methyl lactate

Conditions
ConditionsYield
With Dactylosporangium aurantiacum esterase WDEst9 In aq. buffer at 30℃; for 3h; pH=8.5; Catalytic behavior; Concentration; pH-value; Reagent/catalyst; Solvent; Temperature; Time; Green chemistry; Enzymatic reaction; enantioselective reaction;A n/a
B 86.7%
338-69-2

D-Alanine

10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite82%
With trifluoroacetic acid; sodium nitrite In water at 20℃; for 6h;62%
With sulfuric acid; sodium nitrite In water at 0℃; for 2h;
61597-96-4

Isobutyl (R)-lactate

10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With lithium hydroxide monohydrate In tetrahydrofuran; water at 0 - 20℃; for 48h; Inert atmosphere;77%
338-69-2

D-Alanine

A

10326-41-7

D-Lactic acid

B

4511-42-6

D-lactide

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite In water at 0 - 20℃; stereoselective reaction;A 58%
B < 3 %Spectr.
57-55-6

propylene glycol

10326-41-7

D-Lactic acid

Conditions
ConditionsYield
With phosphate buffer; Gluconobacter oxydans DSM 2003 cells at 28℃; for 20h; pH=6.0;48%
97-64-3, 2676-33-7

ethyl 2-hydroxypropionate

A

79-33-4

L-Lactic acid

B

10326-41-7

D-Lactic acid

C

7699-00-5

(R)-Ethyl lactate

Conditions
ConditionsYield
With ammonium hydroxide at 30℃; pH=6.9;A n/a
B n/a
C 34.5%
77-92-9

citric acid

A

328-42-7

Oxalacetic acid

B

79-33-4

L-Lactic acid

C

10326-41-7

D-Lactic acid

D

513-86-0, 52217-02-4

3-hydroxy-2-butanon

E

64-19-7

acetic acid

F

127-17-3

2-oxo-propionic acid

Conditions
ConditionsYield
With Leuconostoc mesenteroides at 30℃; for 1h; potassium phosphate buffer, pH 5.0; other conditions also investigated; several substrates investigated;A 0.66%
B 0.06%
C 1.77%
D 6.86%
E 15.5%
F 0.05%

(R)-Lactate Chemical Properties

Molecular Structure of Propanoic acid,2-hydroxy-, (2R)- (CAS NO.10326-41-7):

Molecular Formula: C3H6O3
Molecular Weight: 90.0779
IUPAC Name: (2R)-2-Hydroxypropanoic acid
Synonyms of Propanoic acid,2-hydroxy-, (2R)- (CAS NO.10326-41-7): D-Lactic acid ;  (-)-Lactic acid ; (D)-(-)-Lactic acid ; (R)-(-)-Lactic acid ; (R)-2-Hydroxypropanoic acid ; (R)-2-Hydroxypropionsaeure ; (R)-Lactic acid ; (R)-Milchsaeure ; (R)-alpha-Hydroxypropionic acid ; 1-Lactic acid ; D-Milchsaeure ; EINECS 233-713-2 ; Lactic acid (D) ; Propanoic acid, 2-hydroxy-, (2R)- ; Propanoic acid, 2-hydroxy-, (R)-
CAS NO: 10326-41-7
Classification Code: TSCA Flag P [A commenced PMN (Premanufacture Notice) substance] 
Index of Refraction: 1.451
Molar Refractivity: 19 cm3
Molar Volume: 70.5 cm3
Surface Tension: 49.7 dyne/cm
Density: 1.276 g/cm3
Flash Point: 109.9 °C
Enthalpy of Vaporization: 53.96 kJ/mol
Boiling Point: 227.6 °C at 760 mmHg
Vapour Pressure: 0.015 mmHg at 25°C

(R)-Lactate Safety Profile

Hazard Codes of Propanoic acid,2-hydroxy-, (2R)- (CAS NO.10326-41-7): IrritantXi
Risk Statements: 38-41 
R38: Irritating to skin. 
R41: Risk of serious damage to the eyes.
Safety Statements: 26-39 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S39: Wear eye / face protection.
WGK Germany: 3
F: 3-10

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