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Name	2-(2-(2-Aminoethylamino)ethylamino)ethanol	EINECS	N/A
CAS No.	1965-29-3	Density	1.053g/cm³
PSA	70.31000	LogP	-0.40130
Solubility	N/A	Melting Point	N/A
Formula	C6H17 N3 O	Boiling Point	251.9°Cat760mmHg
Molecular Weight	147.22	Flash Point	106.1°C
Transport Information	N/A	Appearance	N/A
Safety	Poison by intraperitoneal route. Moderately toxic by skin contact. Mildly toxic by ingestion. A skin and severe eye irritant. When heated to decomposition it emits toxic fumes of NO_x. See also AMINES.	Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	2-[2-(2-Aminoethylamino)ethylamino]ethanol;8-Amino-3,6-diazaoctanol; Hydroxyethyldiethylenetriamine; Monohydroxyethyldiethylenetriamine;N-(2-Hydroxyethyl)diethylenetriamine; N-(Hydroxyethyl)diethylenetriamine	Article Data	9

2-(2-(2-Aminoethylamino)ethylamino)ethanol Synthetic route

: 75-21-8
oxirane

: 111-40-0
1,5-diamino-3-azapentane

: 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol

Conditions

Conditions	Yield
With water

: 2576-47-8
2-bromoethylamine hydrobromide

: 111-41-1
2-(2-Aminoethylamino)ethanol

: 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol

Conditions

Conditions	Yield
With water

: 111-40-0
1,5-diamino-3-azapentane

: 107-07-3
2-chloro-ethanol

: 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol

Conditions

Conditions	Yield
In water
Stage #1: 3-azapentane-1,5-diamine; 2-chloro-ethanol In water for 8h; Reflux; Stage #2: With potassium carbonate In methanol for 0.5h;

acetate of N--glycine ethyl ester: acetate of N--glycine ethyl ester

: 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol

Conditions

Conditions	Yield
With tetrahydrofuran; lithium aluminium tetrahydride

: 109-99-9
tetrahydrofuran

: 16195-08-7
[2-(2-Amino-acetylamino)-acetylamino]-acetic acid ethyl ester

LiAlH4: LiAlH4

: 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol

Conditions

Conditions	Yield
das Acetat reagiert;

: 107-15-3
ethylenediamine

: 111-42-2
2,2'-iminobis[ethanol]

A: 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol

B: 112-57-2
N-(2-aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine

Conditions

Conditions	Yield
With imidazolidone at 270℃; for 5h; Inert atmosphere;

: 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol

: 5292-43-3
bromoacetic acid tert-butyl ester

: di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)(2-((2-(tert-butoxy)-2-oxoethyl)(2-hydroxyethyl)amino)ethyl)amino)ethyl)azanediyl)diacetate

Conditions

Conditions	Yield
With triethylamine In N,N-dimethyl-formamide at 20℃; for 24h; Inert atmosphere;	60%

: 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol

: 74493-34-8
1,2-dioleoyl-sn-glycero-3-phosphocholine

: dioleoylphosphate-triethylenetriamine

Conditions

Conditions	Yield
With Phospholipase D In ethyl acetate at 40℃; for 72h; Enzymatic reaction;	3%

: 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol

: 5451-98-9
n-octyl chloroacetate

: 51992-90-6
([2-(Bis-octyloxycarbonylmethyl-amino)-ethyl]-{2-[(2-hydroxy-ethyl)-octyloxycarbonylmethyl-amino]-ethyl}-amino)-acetic acid octyl ester

Conditions

Conditions	Yield
With potassium carbonate

: 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol

: 105-39-5
chloroacetic acid ethyl ester

: 51992-89-3
([2-(Bis-ethoxycarbonylmethyl-amino)-ethyl]-{2-[ethoxycarbonylmethyl-(2-hydroxy-ethyl)-amino]-ethyl}-amino)-acetic acid ethyl ester

Conditions

Conditions	Yield
With potassium carbonate

2-(2-(2-Aminoethylamino)ethylamino)ethanol Chemical Properties

IUPAC Name: 2-[2-(2-Aminoethylamino)ethylamino]ethanol
Synonyms: 1,2-Ethanediamine, N-(2-aminoethyl)-N'-(2-hydroxyethyl)- ; Diethylenetriamine, N-(2-hydroxyethyl)- ; Ethanol, 2-((2-((2-aminoethyl)amino)ethyl)amino)- ; Ethanol, 2-[[2-[(2-aminoethyl)amino]ethyl]amino]- ; 2-(2-(2-Aminoethylamino)ethylamino)ethanol
CAS NO: 1965-29-3
Molecular Formula of N-(Hydroxyethyl)diethylenetriamine (CAS NO.1965-29-3) : C₆H₁₇N₃O
Molecular Weight of N-(Hydroxyethyl)diethylenetriamine (CAS NO.1965-29-3) : 147.21868
Molecular Structure of N-(Hydroxyethyl)diethylenetriamine (CAS NO.1965-29-3) :
EINECS: 217-811-2
Mol File: 1965-29-3.mol
Index of Refraction: 1.487
Surface Tension: 41.9 dyne/cm
Density: 1.005 g/cm³
Flash Point: 129 °C
Enthalpy of Vaporization: 61.38 kJ/mol
Boiling Point: 289.7 °C at 760 mmHg
Vapour Pressure: 0.000238 mmHg at 25°C

2-(2-(2-Aminoethylamino)ethylamino)ethanol Uses

N-(Hydroxyethyl)diethylenetriamine (CAS NO.1965-29-3) is used as intermediate in organic synthesis.

2-(2-(2-Aminoethylamino)ethylamino)ethanol Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	320mg/kg (320mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: PERITONITIS	AMA Archives of Industrial Health. Vol. 17, Pg. 129, 1958.
rabbit	LD50	skin	2520uL/kg (2.52mL/kg)		AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rat	LD50	intraperitoneal	146mg/kg (146mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	AMA Archives of Industrial Health. Vol. 17, Pg. 129, 1958.
rat	LD50	oral	4630mg/kg (4630mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	AMA Archives of Industrial Health. Vol. 17, Pg. 129, 1958.

2-(2-(2-Aminoethylamino)ethylamino)ethanol Consensus Reports

Reported in EPA TSCA Inventory.

2-(2-(2-Aminoethylamino)ethylamino)ethanol Safety Profile

Poison by intraperitoneal route. Moderately toxic by skin contact. Mildly toxic by ingestion. A skin and severe eye irritant. When heated to decomposition it emits toxic fumes of NO_x. See also AMINES.

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