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| CAS No.: | 1965-29-3 |
|---|---|
| Name: | 2-(2-(2-aminoethylamino)ethylamino)ethanol |
| Article Data: | 9 |
| Molecular Structure: | |
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| Formula: | C6H17 N3 O |
| Molecular Weight: | 147.22 |
| Synonyms: | 2-[2-(2-Aminoethylamino)ethylamino]ethanol;8-Amino-3,6-diazaoctanol; Hydroxyethyldiethylenetriamine; Monohydroxyethyldiethylenetriamine;N-(2-Hydroxyethyl)diethylenetriamine; N-(Hydroxyethyl)diethylenetriamine |
| Density: | 1.053g/cm3 |
| Boiling Point: | 251.9°Cat760mmHg |
| Flash Point: | 106.1°C |
| Safety: | Poison by intraperitoneal route. Moderately toxic by skin contact. Mildly toxic by ingestion. A skin and severe eye irritant. When heated to decomposition it emits toxic fumes of NOx. See also AMINES. |
| PSA: | 70.31000 |
| LogP: | -0.40130 |
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- 240444-70-62,3,5,6-Tetrafluor-4-(methoxymethyl)benzyl-2,2-dimethyl-3-(prop-1-en-1-yl)cyclopropancarboxylat
| Conditions | Yield |
|---|---|
| With water |
- 2576-47-8
2-bromoethylamine hydrobromide
- 111-41-1
2-(2-Aminoethylamino)ethanol
- 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol
| Conditions | Yield |
|---|---|
| With water |
- 111-40-0
1,5-diamino-3-azapentane
- 107-07-3
2-chloro-ethanol
- 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol
| Conditions | Yield |
|---|---|
| In water | |
| Stage #1: 3-azapentane-1,5-diamine; 2-chloro-ethanol In water for 8h; Reflux; Stage #2: With potassium carbonate In methanol for 0.5h; |
- 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol
| Conditions | Yield |
|---|---|
| With tetrahydrofuran; lithium aluminium tetrahydride |
- 109-99-9
tetrahydrofuran
- 16195-08-7
[2-(2-Amino-acetylamino)-acetylamino]-acetic acid ethyl ester
- 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol
| Conditions | Yield |
|---|---|
| das Acetat reagiert; |
- 107-15-3
ethylenediamine
- 111-42-2
2,2'-iminobis[ethanol]
A
- 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol
B
- 112-57-2
N-(2-aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine
| Conditions | Yield |
|---|---|
| With imidazolidone at 270℃; for 5h; Inert atmosphere; |
| Conditions | Yield |
|---|---|
| With triethylamine In N,N-dimethyl-formamide at 20℃; for 24h; Inert atmosphere; | 60% |
- 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol
- 74493-34-8
1,2-dioleoyl-sn-glycero-3-phosphocholine
| Conditions | Yield |
|---|---|
| With Phospholipase D In ethyl acetate at 40℃; for 72h; Enzymatic reaction; | 3% |
- 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol
- 5451-98-9
n-octyl chloroacetate
- 51992-90-6
([2-(Bis-octyloxycarbonylmethyl-amino)-ethyl]-{2-[(2-hydroxy-ethyl)-octyloxycarbonylmethyl-amino]-ethyl}-amino)-acetic acid octyl ester
| Conditions | Yield |
|---|---|
| With potassium carbonate |
- 1965-29-3
2-[2-(2-aminoethylamino)ethylamino]ethanol
- 105-39-5
chloroacetic acid ethyl ester
- 51992-89-3
([2-(Bis-ethoxycarbonylmethyl-amino)-ethyl]-{2-[ethoxycarbonylmethyl-(2-hydroxy-ethyl)-amino]-ethyl}-amino)-acetic acid ethyl ester
| Conditions | Yield |
|---|---|
| With potassium carbonate |
- Total:32 Page 1 of 1 1
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Chemistry
IUPAC Name: 2-[2-(2-Aminoethylamino)ethylamino]ethanol
Synonyms: 1,2-Ethanediamine, N-(2-aminoethyl)-N'-(2-hydroxyethyl)- ; Diethylenetriamine, N-(2-hydroxyethyl)- ; Ethanol, 2-((2-((2-aminoethyl)amino)ethyl)amino)- ; Ethanol, 2-[[2-[(2-aminoethyl)amino]ethyl]amino]- ; 2-(2-(2-Aminoethylamino)ethylamino)ethanol
CAS NO: 1965-29-3
Molecular Formula of N-(Hydroxyethyl)diethylenetriamine (CAS NO.1965-29-3) : C6H17N3O
Molecular Weight of N-(Hydroxyethyl)diethylenetriamine (CAS NO.1965-29-3) : 147.21868
Molecular Structure of N-(Hydroxyethyl)diethylenetriamine (CAS NO.1965-29-3) : 
EINECS: 217-811-2
Mol File: 1965-29-3.mol
Index of Refraction: 1.487
Surface Tension: 41.9 dyne/cm
Density: 1.005 g/cm3
Flash Point: 129 °C
Enthalpy of Vaporization: 61.38 kJ/mol
Boiling Point: 289.7 °C at 760 mmHg
Vapour Pressure: 0.000238 mmHg at 25°C
Uses
N-(Hydroxyethyl)diethylenetriamine (CAS NO.1965-29-3) is used as intermediate in organic synthesis.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 320mg/kg (320mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: PERITONITIS | AMA Archives of Industrial Health. Vol. 17, Pg. 129, 1958. |
| rabbit | LD50 | skin | 2520uL/kg (2.52mL/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951. | |
| rat | LD50 | intraperitoneal | 146mg/kg (146mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | AMA Archives of Industrial Health. Vol. 17, Pg. 129, 1958. |
| rat | LD50 | oral | 4630mg/kg (4630mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | AMA Archives of Industrial Health. Vol. 17, Pg. 129, 1958. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Poison by intraperitoneal route. Moderately toxic by skin contact. Mildly toxic by ingestion. A skin and severe eye irritant. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.