Hot Products

Basic Information

Post buying leads

Suppliers

Cas Database

Name	2,3-Dichloropyrazine	EINECS	225-460-1
CAS No.	4858-85-9	Density	1.493 g/cm³
PSA	25.78000	LogP	1.78340
Solubility	N/A	Melting Point	22.5-24.5 °C
Formula	C₄H₂Cl₂N₂	Boiling Point	190.6 °C at 760 mmHg
Molecular Weight	148.979	Flash Point	86.1 °C
Transport Information	N/A	Appearance	clear colorless to light yellow liquid
Safety	36/37/39-26-36	Risk Codes	36/37/38-20/21/22
Molecular Structure		Hazard Symbols	Xn, Xi
Synonyms	Pyrazine,2,3-dichloro-;	Article Data	17

2,3-Dichloropyrazine Synthetic route

: 14508-49-7
2-chloropyrazin

: 4858-85-9
2,3-dichloropyrazine

Conditions

Conditions	Yield
Stage #1: 2-chloropyrazin With 2,2,6,6-tetramethyl-piperidine; n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Stage #2: With hexachloroethane In tetrahydrofuran; hexane at -78℃; for 1h;	90%
With sulfuryl dichloride In N,N-dimethyl-formamide	81%

: 931-18-0
2,3-dihydroxypirazine

: 4858-85-9
2,3-dichloropyrazine

Conditions

Conditions	Yield
With trichlorophosphate	84%

: 6863-76-9
3-chloropyrazine 1-oxide

A: 19745-07-4
2,5-dichloropyrazine

B: 4858-85-9
2,3-dichloropyrazine

C: 4774-14-5
2,6-dichloropyrazine

Conditions

Conditions	Yield
With trichlorophosphate for 2h; Heating; Yield given. Yields of byproduct given;
With 1,8-diazabicyclo[5.4.0]undec-7-ene; trichlorophosphate for 2h; Heating; Yield given. Yields of byproduct given;

: 2423-84-9
Pyrazin-N.N'-dioxyd

A: 4858-85-9
2,3-dichloropyrazine

B: 4774-14-5
2,6-dichloropyrazine

Conditions

Conditions	Yield
With trichlorophosphate for 2h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

: 6863-76-9
3-chloropyrazine 1-oxide

A: 14508-49-7
2-chloropyrazin

B: 19745-07-4
2,5-dichloropyrazine

C: 4858-85-9
2,3-dichloropyrazine

D: 4774-14-5
2,6-dichloropyrazine

Conditions

Conditions	Yield
With trichlorophosphate for 2h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

: 16025-16-4
2-chloropyrazine 1-oxide

A: 14508-49-7
2-chloropyrazin

B: 4858-85-9
2,3-dichloropyrazine

C: 4774-14-5
2,6-dichloropyrazine

Conditions

Conditions	Yield
With trichlorophosphate for 2h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

: 14508-49-7
2-chloropyrazin

A: 4858-85-9
2,3-dichloropyrazine

B 2,6-dichloro-pyrazine and 2,5-dichloro-pyrazine: 2,6-dichloro-pyrazine and 2,5-dichloro-pyrazine

Conditions

Conditions	Yield
With chlorine at 475℃;

: 290-37-9
1,4-pyrazine

: 7732-18-5
water

: 7782-50-5
chlorine

A: 14508-49-7
2-chloropyrazin

B: 19745-07-4
2,5-dichloropyrazine

C: 4858-85-9
2,3-dichloropyrazine

D: 4774-14-5
2,6-dichloropyrazine

Conditions

Conditions	Yield
at 350℃; Product distribution;

...Expand

: 290-37-9
1,4-pyrazine

A: 4858-85-9
2,3-dichloropyrazine

B chloropyrazine, 2,6-dichloro-pyrazine, 2,5-dichloro-pyrazine: chloropyrazine, 2,6-dichloro-pyrazine, 2,5-dichloro-pyrazine

Conditions

Conditions	Yield
With water; chlorine at 350℃;
With water; chlorine at 400 - 500℃;
With water; chlorine at 400 - 500℃;

: 6863-76-9
3-chloropyrazine 1-oxide

: 4858-85-9
2,3-dichloropyrazine

Conditions

Conditions	Yield
With trichlorophosphate at 60℃; for 1h; Heating / reflux;

2,3-Dichloropyrazine Chemical Properties

Molecular structure of 2,3-Dichloropyrazine (CAS NO.4858-85-9) is:

Product Name: 2,3-Dichloropyrazine
CAS Registry Number: 4858-85-9
IUPAC Name: 2,3-dichloropyrazine
Molecular Weight: 148.97808 [g/mol]
Molecular Formula: C₄H₂Cl₂N₂
XLogP3-AA: 1.7
H-Bond Donor: 0
H-Bond Acceptor: 2
EINECS: 225-460-1
Melting point: 22.5-24.5 °C
Surface Tension: 51.5 dyne/cm
Density: 1.493 g/cm³
Flash Point: 86.1 °C
Enthalpy of Vaporization: 40.93 kJ/mol
Boiling Point: 190.6 °C at 760 mmHg
Vapour Pressure: 0.745 mmHg at 25°C
Product Categories: Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines;Piperazine series;API intermediates;Pyrazines;Chloropyrazines, etc.;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;PyrazinesHeterocyclic Building Blocks

2,3-Dichloropyrazine Uses

2,3-Dichloropyrazine (CAS NO.4858-85-9) is used for pharmaceutical intermediates.

2,3-Dichloropyrazine Safety Profile

Safty information about 2,3-Dichloropyrazine (CAS NO.4858-85-9) is:
Hazard Codes: Harmful Xn,Xi
Risk Statements: 36/37/38-20/21/22
R36/37/38:Irritating to eyes, respiratory system and skin.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 36/37/39-26-36
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
Hazard Note: Irritant
HazardClass: IRRITANT

2,3-Dichloropyrazine Specification

2,3-Dichloropyrazine (CAS NO.4858-85-9) is a clear colorless to light yellow liquid.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 4858-85-9