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4-AMINOANTIPYRINE

  • Name 4-AMINOANTIPYRINE
  • EINECS201-452-3
  • CAS No. 83-07-8
  • Density1.207 g/cm3
  • PSA52.95000
  • LogP1.64780
  • Solubilitywater: 0.1 g/mL, clear
  • Melting Point105-110 °C(lit.)
  • FormulaC11H13N3O
  • Boiling Point309 °C at 760 mmHg
  • Molecular Weight203.244
  • Flash Point140.7 °C
  • Transport InformationN/A
  • AppearanceAmber crystalline powder
  • Safety26-36-36/37/39
  • Risk Codes22-36/37/38-20/21/22
  • Molecular Structure
    Molecular Structure of 83-07-8 (4-Aminoantipyrine)
  • Hazard SymbolsHarmfulXn
  • SynonymsHarmfulXn
  • Article Data37

4-AMINOANTIPYRINE Chemical Properties

IUPAC Name: 4-Aminoantipyrine
The MF of 4-Aminoantipyrine (83-07-8) is C11H13N3O.

                    
The MW of 4-Aminoantipyrine (83-07-8) is 203.24.
Synonyms of 4-Aminoantipyrine (83-07-8): 4-Amino-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one ; 4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one ; 4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one
Product Categories: Drug bulk;Pyridines, Pyrimidines, Purines and Pteredines
Form: amber crystalline powder
Index of Refraction: 1.606
EINECS: 201-452-3   
Density: 1.207 g/ml 
Flash Point: 140.7 °C 
Boiling Point: 309 °C
Melting Point: 107-109 °C
Storage temp: Store at RT
Water Solubility: 500 g/L (20 ºC)
Merck: 14,591
BRN: 181635
Stability: Stable

4-AMINOANTIPYRINE Uses

  4-Aminoantipyrine (83-07-8) is pharmaceutical intermediates analgin used to test alcohol and amines, phenols measured air and water.

4-AMINOANTIPYRINE Toxicity Data With Reference

1.    

mmo-sat 5 µmol/plate

    MUREAV    Mutation Research. 206 (1988),317.
2.    

dnr-esc 312 µg/well

    MUREAV    Mutation Research. 133 (1984),161.
3.    

orl-rat LD50:1700 mg/kg

    BCFAAI    Bollettino Chimico Farmaceutico. 117 (1978),638.
4.    

ipr-rat LD50:1200 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 99 (1950),171.
5.    

orl-mus LD50:800 mg/kg

    CCCCAK    Collection of Czechoslovak Chemical Communications. 47 (1982),636.
6.    

ipr-mus LD50:270 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 10 (1960),820.

4-AMINOANTIPYRINE Consensus Reports

Reported in EPA TSCA Inventory.

4-AMINOANTIPYRINE Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.
Safety information of 4-Aminoantipyrine (83-07-8):
Hazard Codes  Xn
Risk Statements 
36/37/38  Irritating to eyes, respiratory system and skin
20/21/22  Harmful by inhalation, in contact with skin and if swallowed
Safety Statements 
26  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39  Wear suitable protective clothing, gloves and eye/face protection
WGK Germany  3
RTECS  CD2480000
F  8-9-23
Hazard Note  Harmful
HS Code  29331190

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