10359-09-8

Basic information

• Product Name: 2-(4-chlorophenyl)-1,3-dithiane
• CAS NO: 10359-09-8
• Molecular Formula: C₁₀H₁₁ClS₂
• Molecular Weight: 230.7773
• Mol File: 10359-09-8.mol

Chemical Properties

• Boiling Point: 355.5°C at 760 mmHg
• Flash Point: 158.7°C
• Density: 1.271g/cm³
• Vapor Pressure: 6.4E-05mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: 2-(4-chlorophenyl)-1,3-dithiane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-1,3-dithiane(10359-09-8)
• EPA Substance Registry System: 2-(4-chlorophenyl)-1,3-dithiane(10359-09-8)

Safety Data

• Hazardous Substances Data: 10359-09-8(Hazardous Substances Data)

Usage

Dithiane derivative

a compound derived from a dithiane ring, which is a six-membered ring containing two sulfur atoms.

Six-membered ring

the dithiane ring in 2-(4-chlorophenyl)-1,3-dithiane, which consists of six atoms.

Chlorine-substituted phenyl group

a phenyl group (a six-membered ring with alternating single and double bonds) that has a chlorine atom attached to it, which is a common feature in many pharmaceuticals and agrochemicals.

Building block in organic synthesis

2-(4-chlorophenyl)-1,3-dithiane is a commonly used compound in organic synthesis, often utilized as a starting material for the preparation of more complex organic molecules.

Versatile reactivity and stability

the compound's ability to react with a wide range of other chemicals and its resistance to decomposition make it a valuable tool in the development of new chemical compounds in medicinal chemistry and drug discovery.

Upstream product

• 544-25-2 Cyclohepta-1,3,5-triene 
• 86201-65-2 2-(4-Chlorphenyl)-1,3-dithian-2-ylium-tetrafluoroborat 
• 74-11-3 para-chlorobenzoic acid 
• 109-80-8 1.3-propanedithiol 
• 2403-61-4 p-chlorobenzaldehyde diethyl acetal 
• 6413-52-1 2-(4-chloro-phenyl)-[1,3]dioxane 
• 13086-93-6 (acetyloxy)(4-chlorophenyl)methyl acetate 
• 35583-10-9 3,9-di(p-chlorophenyl)-2,4,8,10-tetraoxaspiro[5.5]undecane 
• 3848-36-0 4-chlorobenzaldoxime 
• 104-88-1 4-chlorobenzaldehyde 
• 55727-23-6 3‐(1,3-dithiane-2-yl)pentane-2,4-dione 
• 2403-54-5 2-(4-chlorophenyl)-1,3-dioxolane 
• 67-56-1 methanol 
• 682360-46-9 2-(1,3-dithian-2-ylidene)-3-oxobutanoic acid 

Downstream Products

• 6573-59-7 1,2,6,7-tetrathiacyclodecane 
• 104-88-1 4-chlorobenzaldehyde 
• 111997-81-0 2-(4-Chlorphenyl)-1,3-dithian-2-ylium-tribromid 
• 3395-81-1 4-chlorobenzaldehyde dimethyl acetal 
• 254973-56-3 2-(4-Chlorophenyl)-2-(trimethylsilyl)-1,3-dithiane 
• 639820-90-9 2-[2-(4-chloro-phenyl)-[1,3]dithian-2-ylmethyl]-1-methyl-piperidine 
• 461051-86-5 2-(4-chlorophenyl)-2-triethylsilyl-1,3-dithiane 
• 461051-93-4 4-chlorophenyl triethylsilyl ketone 
• 1048379-35-6 potassium (2-(4-chloro-phenyl)-1,3-dithian-2-yl)trifluoroborate 
• 1127955-53-6 2-(2-bromobenzyl)-2-(4-chlorophenyl)-1,3-dithiane 
• 1243701-42-9 C₁₅H₁₉ClOS₂ 
• 51445-67-1 1-(4-chlorophenyl)butane-1,2-dione 
• 1279712-78-5 (Z)-N-(1-(4-chlorophenyl)-1-oxobut-2-en-2-yl)acetamide 
• 1279712-70-7 C₁₃H₁₇ClOS₂ 

Relevant articles and documents

An uncommon use of irradiated flavins: Br?nsted acid catalysis

We present that thioacetalization of aldehydes can be induced by blue light irradiation in the presence of a catalytic amount of riboflavin tetraacetate (RFTA) under aerobic conditions. Several control experiments have suggested that the reaction is more

Perchloric acid adsorbed on silica gel (HClO4-SiO2) as an extremely efficient and reusable catalyst for 1,3-dithiolane/dithiane formation

Perchloric acid adsorbed on silica gel (HClO4-SiO2) has been found to be an extremely efficient and reusable catalyst for 1,3-dithiolane and 1,3-dithiane formation under solvent-free conditions at room temperature. Georg Thieme Verla

Trichloroisocyanuric acid as a mild and efficient catalyst for thioacetalization and transthio-acetalization reactions

Trichloroisocyanuric acid (1), a cheap industrial chemical, catalyzes mild and efficient thioacetalization and transthioacetalization reactions. In addition, this catalyst is very selective for this purpose.

Lithium trifluoromethanesulfonate (LiOTf) as a highly efficient catalyst for chemoselective dithioacetalization of carbonyl compounds under neutral and solvent-free conditions

Various types of carbonyl compound can be efficiently and chemoselectively converted to their corresponding dithioacetals in the presence of catalytic amounts of lithium triflate under solvent-free conditions. Due to the neutrality of the reaction medium, this method is especially useful for acid sensitive substrates.

Investigations towards the chemoselective thioacetaliztion of carbonyl compounds by using ionic liquid [bmim]Br as a recyclable catalytic medium

The ionic liquid based on the 1-n-butyl-3-methylimidazolium cation has been prepared and used as an efficient catalytic medum for the chemoselective thioacetalization of carbonyl compounds. Furthermore, recycling and reuse of this ionic liquid medium has

1,3-dibromo-5,5-dimethylhydantoin (DBH) as a mild and efficient catalyst for chemoselective thioacetalization of carbonyl compounds and dethioacetalization under mild conditions

Hydantoin bromide is an effective catalyst for chemoselective thioacetalization of aldehydes in the presence of ketones under neutral conditions. In addition, a simple and efficient procedure for the deprotection of 1,3-dithianes and 1,3-dithiolanes of ar

Mesoporous sBa-15 silica catalyst functionalized with phenylsulfonic acid groups (SbA-15-ph-So3h) as efficient nanocatalyst for chemoselective thioacetalization of carbonyl compounds

In this research a Nano acidic catalyst was prepared and its efficiency on thioacetalization of carbonyl compounds was examined. For this aim we used modified SBA-15 as support, which have been modified by phenolic and sulfonic acid. SBA-15 is a member of

Highly efficient transthioacetalization of O,O-acetals catalyzed by indium(III) chloride

A simple, efficient and general procedure has been developed for the transthioacetalization of O,O-acetals catalyzed by indium(III) chloride in 1,2-dichloroethane.

Molybdenum pentachloride (MoCl5) catalyzes efficient dithioacetalization of carbonyl compounds and transdithioacetalization of O, O-acetals. This catalyst also conducts efficient non-hydrolytic deprotection of dithioacetals in the presence of dry DMSO. Part 2

Dithioacetalization of carbonyl compounds was performed efficiently in CH2Cl2 at room temperature in the presence of MoCl5. Highly selective transdithioacetalization of acetals was also catalyzed efficiently by this catalyst. MoCl5 performed non-hydrolytic deprotection of dithioacetals in the presence of dry DMSO.

Chemoselective and odorless transthioacetalization of acetals using α-oxo-ketene dithioacetals as thiol equivalents

Using α-oxo-ketene dithioacetals 1a as odorless thiol equivlents, an efficient and odorless transthioacetalization of acetals 2 has been developed. In the presence of MeCOCl in MeOH, the cleavage of 1a commences to generate thiols at both room and reflux temperatures, and the generated thiols then react with acetals 2 to give correspecting thioacetals 3 in good yield. This transthioacetalization is characterized by mild reaction conditions, simple procedure, good yields, and perfect chemoselectivity. It is noteworthy that only a very faint odor of thiols can be perceived during both the reaction and workup.