13086-93-6

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 108-24-7 acetic anhydride 
• 116274-78-3 6-(4-Chloro-phenyl)-6,7-dihydro-5H-5,7,7a,13-tetraaza-benzo[3,4]cyclohepta[1,2-b]naphthalen-8-one 
• 3395-81-1 4-chlorobenzaldehyde dimethyl acetal 
• 6283-10-9 2-(4-chlorophenyl)-5,5-dimethyl-1,3-dioxane 
• 540-63-6 ethane-1,2-dithiol 
• 555-16-8 4-nitrobenzaldehdye 
• 100-52-7 benzaldehyde 
• 106-43-4 para-chlorotoluene 
• 64-19-7 acetic acid 

Downstream Products

• 5333-82-4 2,2,2-trichloro-1-(4-chloro-phenyl)-ethanol 
• 623-03-0 4-Cyanochlorobenzene 
• 77415-40-8 1-(4-Chlorophenyl)-1-propyl acetate 
• 104-88-1 4-chlorobenzaldehyde 
• 958-06-5 (+/-)-(4-chlorophenyl)(phenyl)methyl acetate 
• 103966-61-6 1-(4-chlorophenyl)ethyl acetate 
• 89978-12-1 2-chloro-2-(4-chlorophenyl)acetonitrile 
• 99074-23-4 cyano(4-chlorophenyl)methyl acetate 
• 10359-09-8 2-(4-chlorophenyl)-1,3-dithiane 
• 35583-10-9 3,9-di(p-chlorophenyl)-2,4,8,10-tetraoxaspiro[5.5]undecane 
• 5406-33-7 4-chlorobenzyl acetate 
• 23229-32-5 2-(4-chlorophenyl)-1,3-dithiolane 
• 14506-33-3 1-(4-chlorophenyl)but-3-en-1-ol 
• 205999-88-8 5-methoxycarbonyl-6-methyl-4-(4-chlorophenyl)-3,4-dihydropyrimidin-2(1H)-one 

Relevant academic research and scientific papers

NbCl5 as an efficient catalyst for chemoselective synthesis of 1,1-diacetates under solvent-free conditions

A mild and efficient method for the chemoselective preparation of 1,1-diacetates catalyzed by NbCl5(5mmol%) under solvent-free conditions has been developed. The yields are in the range of 93-98%. This protocol offered several advantages, including low catalyst loading, good yields, short reaction times, and environmentally friendliness.

Indium tribromide as a highly efficient and versatile catalyst for chemoselective synthesis of acylals from aldehydes under solvent-free conditions

A mild and efficient method has been developed for the chemoselective preparation of acylals from aldehydes in the presence of catalytic amounts (0.01-1.0 mol%) of InBr3 under solvent-free conditions in very good to excellent yields.

Solvent-free catalytic preparation of 1,1-diacetates using a silica-supported functional ionic liquid as catalyst

An efficient and convenient preparation of acylals from aldehydes and acetic anhydride, under solvent-free conditions, in the presence of a silica-supported functional ionic liquid, Si-[SbSipim][PF6], is reported. Si-[SbSipim][PF6] acts as a catalyst and can be recovered and reused four times without apparent loss of its catalytic activity.

A rapid and convenient synthesis of 1,1-diacetates from aldehydes and acetic anhydride catalyzed by PVC-FeCl3 catalyst

A variety of aldehydes can be converted into 1,1-diacetates rapidly and conveniently in the presence of catalytic amounts of poly(vinyl chloride) supported ferric chloride reagent at room temperature in excellent yields.

1,3-Dibromo-5,5-dimethylhydantoin as catalyst for the conversion of aldehydes to their 1,1-diacetates (acetylals) under solvent-free and neutral conditions

Highly efficient and mild acetylation of aldehydes with acetic anhydride catalysed by 1,3-dibromo-5,5-dimethylhydantoin (DBH) was performed under neutral conditions to produce corresponding 1,1-diacetates (acetylals) in good to excellent yields.

An efficient method for the chemoselective synthesis of acylals from aromatic aldehydes using bismuth triflate

Aromatic aldehydes are smoothly converted into the corresponding acylals in good yields in the presence of 0.10 mol% Bi(OTf)3·xH2O. Ketones are not affected under the reaction conditions. The highly catalytic nature of bismuth triflate and the fact that it is relatively non-toxic, easy to handle and insensitive to small amounts of air and moisture makes this procedure especially attractive for large-scale synthesis.

A rapid preparation of acylals of aldehydes catalysed by Fe3+- montmorillonite

Aldehydes can be converted to acylals by treatment with acetic anhydride in the presence of Fe3+-montmorillonite in excellent yield at room temperature.

A novel and efficient conversion of aldehydes to 1,1-diacetates catalyzed with FeCl3/SiO2 under microwave irradiation

1,1-Diacetates (3) are effectively synthesized in few minutes by acylation reaction of aldehydes with acetic anhydride in the presence of FeCl3/SiO2 under microwave irradiation.

Synthesis of 1,1-Diacetates from Aldehydes using Trimethylchlorosilane and Sodium Iodide as Catalyst

A variety of aldehydes react with acetic anhydride in the presence of trimethylchlorosilane and sodium iodide or trimethylchlorosilane alone to afford 1,1-diacetates in excellent yields.

A convenient and efficient protocol for the synthesis of acylals catalyzed by Br?nsted acidic ionic liquids under ultrasonic irradiation

The synthesis of acylals (1,1-diacetates) via the reactions of aldehydes with acetic anhydride was carried out in 85-97% yields at room temperature under ultrasound irradiation catalyzed by the Br?nsted acidic ionic liquid [bmpy]HSO4. This method provides several advantages, such as solvent-free conditions, operational simplicity, higher yields, and reduced environmental consequences. The ionic liquid was recovered and reused.