16002-63-4

Basic information

• Product Name: PHENYLMAGNESIUM IODIDE
• Synonyms: PHENYLMAGNESIUM IODIDE;42%inethyletherca.2mol/L;Phenylmagnesium Iodide (42% in Ethyl Ether, ca. 2mol/L);Phenyliodomagnesium;PhenylMagnesiuM Iodide PhenylMagnesiuM Iodide (ca. 42% in Ethyl Ether, ca. 2Mol/L);Phenylmagnesium iodide, 0.50 M in THF
• CAS NO: 16002-63-4
• Molecular Formula: C₆H₅IMg
• Molecular Weight: 228.31
• Product Categories: Classes of Metal Compounds;Grignard Reagents;Grignard Reagents & Alkyl Metals;Mg (Magnesium) Compounds;Synthetic Organic Chemistry;Typical Metal Compounds;Pharm intermediate
• Mol File: 16002-63-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: PHENYLMAGNESIUM IODIDE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYLMAGNESIUM IODIDE(16002-63-4)
• EPA Substance Registry System: PHENYLMAGNESIUM IODIDE(16002-63-4)

Safety Data

• RIDADR: UN 2924 3/8/PG I
• HazardClass: 3/8
• PackingGroup: I
• Hazardous Substances Data: 16002-63-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Phenylmagnesium iodide is used as a nucleophilic agent for the formation of carbon-carbon bonds, which is crucial in the synthesis of complex organic molecules. Its ability to form aryl-aryl, aryl-alkyl, and aryl-heteroatom bonds makes it a valuable reagent in constructing molecular frameworks.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, phenylmagnesium iodide is utilized as a key intermediate in the synthesis of various drugs. Its reactivity allows for the creation of specific molecular structures that are essential for the development of new medicinal compounds.
Used in Natural Product Synthesis:
Phenylmagnesium iodide is employed as a synthetic building block in the preparation of natural products. Its versatility in forming different types of carbon-carbon bonds is particularly useful in mimicking the complex structures found in natural substances.
Used in Academic Research:
In academic research, phenylmagnesium iodide is used as a tool to explore new reaction pathways and mechanisms in organic chemistry. Its reactivity provides opportunities for studying the fundamental principles of chemical bond formation and the development of novel synthetic methods.

InChI:InChI=1/C6H5.HI.Mg/c1-2-4-6-5-3-1;;/h1-5H;1H;/q;;+1/p-1/rC6H5IMg/c7-8-6-4-2-1-3-5-6/h1-5H

Upstream product

• 591-50-4 iodobenzene 
• 60-29-7 diethyl ether 
• 3124-01-4 hexaphenyl diplumbane 
• 71-43-2 benzene 

Downstream Products

• 29909-72-6 3-Phenylbenzofuran 
• 100-52-7 benzaldehyde 
• 4222-20-2 3,3-diphenyl-3H-naphtho[2,1-b]pyran 
• 92-52-4 biphenyl 
• 139-66-2 diphenyl sulfide 
• 618-41-7 Benzenesulfinic acid 
• 882-33-7 diphenyldisulfane 
• 76-84-6 triphenylmethyl alcohol 
• 5333-62-0 benzyl trityl ether 
• 65-85-0 benzoic acid 
• 100-51-6 benzyl alcohol 
• 108-95-2 phenol 
• 6201-08-7 10,10'-Dibenzoyl-9,10,9',10'-tetrahydro-[9,9']bianthryl 
• 119-53-9 2-hydroxy-2-phenylacetophenone 

Relevant articles and documents

An N-Fluorinated Imide for Practical Catalytic Imidations

Catalytic imidation using NFSI as the nitrogen source has become an emerging tool for oxidative carbon-nitrogen bond formation. However, the less than ideal benzenesulfonimide moiety is incorporated into products, severely detracting its synthetic value.

Efficient C(sp3)-H bond functionalization of isochroman by azadol catalysis

A novel organocatalytic C(sp3)-H bond functionalization of isochroman under practical conditions has been developed. In the presence of 5.0 mol % of AZADOL, the catalysis proceeded successfully with a broad range of substrates and nucleophiles in excellent yields.

PLATINUM COMPLEXES

The invention aims at providing platinum complexes useful as materials for light emitting devices and extremely excellent in heat stability, luminous characteristics, and luminous efficiency, and a process for effective preparation thereof. The invention relates to platinum complexes represented by the general formula [1]: wherein any two of A, B and C are each independently an optionally substituted nitrogenous aromatic heterocyclic group and the other is optionally substituted aryl or optionally substituted heteroaryl; and Y is halogeno or an optionally substituted aryl or heteroaryl group which is bonded either directly or through oxygen (-O-) or sulfur (-S-) (with the proviso that when the adjacent two rings are nitrogenous aromatic heterocyclic groups, the cases wherein Y is chloro are excepted, while when the nonadjacent two rings are nitrogenous aromatic heterocyclic groups, the cases wherein Y is not halogeno are excepted).

Nodulisporic acid derivatives

The present invention relates to novel nodulosporic acid derivatives, which are acaricidal, antiparasitic, insecticidal and anthelmintic agents.

Kinetics and Thermodynamics of Oxidation of Magnesium with Phenyl Halides in Benzene in the Presence of Diethyl Ether

The equilibrium constants and the enthalpies and entropies of adsorption of phenyl chloride and phenyl iodide on the surface of magnesium during oxidation in benzene were determined. The reaction scheme explaining acceleration of conversion and increase in the fraction of products of the Wuertz reaction with increasing concentration of oxidant was suggested.

OXIDATION OF METALLIC MAGNESIUM WITH ARYL HALIDES IN DIPOLAR APROTIC SOLVENTS

The dependence of the specific rate of oxidation of metallic magesium with aryl halides on the donor number of the ligand used has an extremum character.This demonstrates the selectivity of adsorption of the complexing agent participating in the process o