16413-89-1

Basic information

• Product Name: Cobaltous chloride Co 57
• Synonyms: Cobaltous chloride Co 57;cobalt(+2) cation dichloride
• CAS NO: 16413-89-1
• Molecular Formula: Cl2Co
• Molecular Weight: 0
• Mol File: 16413-89-1.mol

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 33900mmHg at 25°C
• CAS DataBase Reference: Cobaltous chloride Co 57(CAS DataBase Reference)
• NIST Chemistry Reference: Cobaltous chloride Co 57(16413-89-1)
• EPA Substance Registry System: Cobaltous chloride Co 57(16413-89-1)

Safety Data

• Hazardous Substances Data: 16413-89-1(Hazardous Substances Data)

Usage

InChI:InChI=1/2ClH.Co/h2*1H;/q;;+2/p-2/i;;1-2

Upstream product

• 7440-48-4 cobalt 
• 759403-02-6 cobalt(II) carbonate 
• 1112-67-0 tetrabutyl-ammonium chloride 
• 7782-50-5 chlorine 
• 12052-42-5 cobalt antimonide 
• 10025-91-9 antimony(III) chloride 
• 10545-99-0 sulfur dichloride 
• 56-23-5 tetrachloromethane 
• 98-87-3 benzylidene dichloride 
• 71-48-7 cobalt(II) acetate 
• 75-36-5 acetyl chloride 
• 7647-01-0 hydrogenchloride 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 243459-59-8 Co(C₄₈H₂₈N₈) 
• 243459-72-5 Co(C₄₈H₂₈N₈) 
• 7773-01-5 manganese(ll) chloride 
• 26040-38-0 Co(C₄H₇N₂O₂)2(H₂NC₆H₅)2⁽¹⁺⁾*Cl^(1-)=[Co(C₄H₇N₂O₂)2(H₂NC₆H₅)2]Cl 
• 15218-68-5 Co(C₄H₇N₂O₂)2(H₂NC₆H₄OCH₃)2⁽¹⁺⁾*Cl^(1-)=[Co(C₄H₇N₂O₂)2(H₂NC₆H₄OCH₃)2]Cl 
• 22541-63-5 cobalt(III) 
• 84042-70-6 bis(2,4-pentanedionedihydrazone)cobalt(II) chloride 
• 78654-06-5 (C₂H₅)4N⁽¹⁺⁾*Co(P(C₆H₅)3)Cl₂Br^(1-)=(C₂H₅)4N[Co(P(C₆H₅)3)Cl₂Br] 

Relevant articles and documents

Mixed-Ligand Cobalt(III) Complexes of a Naturally Occurring Coumarin and Phenanthroline Bases as Mitochondria-Targeted Dual-Purpose Photochemotherapeutics

The bioessential nature of cobalt and the rich photochemistry of its coordination complexes can be exploited to develop potential next-generation photochemotherapeutics. A series of six novel mixed-ligand cobalt(III) complexes of the formulation [Co(B)2(L)]ClO4 (1-6), where B is an N,N-donor phenanthroline base, namely, 1,10-phenanthroline (phen in 1 and 4), dipyrido[3,2-d:2′,3′-f]quinoxaline (dpq in 2 and 5), and dipyrido[3,2-a:2′,3′-c]phenazine (dppz in 3 and 6), and L is an O,O-donor dianionic ligand derived from catechol (1,2-dihydroxybenzene, cat2-, in 1-3) or esculetin (6,7-dihydoxycoumarin, esc2-, in 4-6), have been prepared and characterized, and their light-triggered cytotoxicity has been studied in cancer cells. The single-crystal X-ray diffraction structures of complexes 1 (as PF6- salt, 1a) and 2 show distorted octahedral geometries around the cobalt(III) center formed by the set of N4O2 donor atoms. The low-spin and 1:1 electrolytic complexes 1-6 display a d-d transition around 700 nm. Complexes 4-6 with a coordinated esc2- ligand additionally display a π→ π? intraligand transition centered at 403 nm. Complexes 4-6 possessing a naturally occurring and photoactive esc2- ligand show high visible-light-triggered cytotoxicity against HeLa and MCF-7 cancer cells, yielding remarkably low micromolar IC50 values while being much less toxic under dark conditions. Control complexes 1-3 possessing the photoinactive cat2- ligand show significantly less cytotoxicity either in the presence of light or in the dark. The complex-induced cell death is apoptotic in nature caused by the formation of reactive oxygen species via a type 1 photoredox pathway. Fluorescence microscopy of HeLa cells treated with complex 6 reveals mitochondrial localization of the complex. A significant decrease in the dark toxicity of free esculetin and dppz base is observed upon coordination to cobalt(III). Complexes bind to calf-thymus DNA with significant affinity, but 6 binds with the greatest affinity. Complex 6 efficiently photocleaves supercoiled DNA to its nicked circular form when irradiated with visible light via a photoredox type 1 pathway involving hydroxyl radicals (HO?). Thus, complex 6 showing remarkable visible-light-triggered cytotoxicity but negligible toxicity in the dark is a good candidate for cancer photochemotherapy applications.

Synthesis, molecular, and crystal structures of 3d transition metal cyanocyclopentadienides [M(MeOH)n(H2O)4-n{C5(CN)4X}2] (M=Mn, Fe, Co, Ni, Cu, Zn; X=H, CN, NH2, NO

The reaction of the 3d transition metal dichlorides MCl2 (M=Mn, Fe, Co, Ni, Cu, Zn) with the silver salts of substituted tetracyanocyclopentadienides Ag+ [C5(CN)4X]- (X=CN, H, NH2 NO2

Cobalt Oxide Materials for Oxygen Evolution Catalysis via Single-Source Precursor Chemistry

The utilization of metal alkoxides as single-source precursors for (mixed-)oxide materials offers remarkable benefits, such as the possibility to precisely control the metal ratio in the resulting material, highly homogeneous distribution of the elements in the film, and the low temperatures required for film processing. Herein we report on the isolation and characterization of the bimetallic Co-Mo alkoxide [Co3Mo4O10(OCH3)10(dmf)4] (Co3Mo4; dmf=N,N-dimethylformamide), which was prepared by the anion metathesis reaction of the corresponding metal chlorides. The Co-Mo alkoxide was explored as a well-defined precursor of cobalt oxide catalysts for the oxygen evolution reaction (OER) in alkaline electrolyte MOH. The catalysts demonstrated excellent activity in the OER, manifested in low onset potentials and Tafel slopes and superb stability under the operating conditions both in alkaline and nearly neutral media. It was observed that the nature of the metal cation of the alkaline electrolyte MOH (M+=Li+, Na+, K+, Cs+) greatly affected the catalytic performance of the material. We propose that the positive effect of larger metal cations on the film activity in the OER could be explained by the higher hydration enthalpies of larger ions and enhanced mass transport within a larger interlayer space between the [CoO2]δ?∞ sheets of the in situ formed binary oxides. It may be deduced that this trend is universal and may be extended to other types of metal oxides forming layered structures during the OER.

Bis(dinitrogen)cobalt(-1) Complexes with NHC Ligation: Synthesis, Characterization, and Their Dinitrogen Functionalization Reactions Affording Side-on Bound Diazene Complexes

Late-transition-metal-based catalysts are widely used in N2 fixation reactions, but the reactivity of late-transition-metal N2 complexes, besides iron N2 complexes, has remained poorly understood as their N2 complexes were thought to be labile and hard to functionalize. By employing a monodentate N-heterocyclic carbene (NHC), 1,3-dicyclohexylimidazol-2-ylidene (ICy) as ligand, the cobalt(0)- and cobalt(-1)-N2 complexes, [(ICy)3Co(N2)] (1) and [(ICy)2Co(N2)2M]n (M = K, 2a; Rb, 2b; Cs, 2c), respectively, were synthesized from the stepwise reduction of (ICy)3CoCl by the corresponding alkaline metals under a N2 atmosphere. Complexes 2a-c in their solid states adopt polymeric structures. The N-N distances (1.145(6)-1.162(5) ?) and small N-N infrared stretchings (ca. 1800 and 1900 cm-1) suggest the strong N2 activation of the end-on N2 ligands in 2a-c. One electron oxidation of 1 by [Cp2Fe][BF4] gave the cobalt(I) complex devoid of N2 ligand [(ICy)3Co][BF4] (3). The bis(dinitrogen)cobalt(-1) complexes 2a-c undergo protonation reaction with triflic acid to give N2H4 in 24-30% yields (relative to cobalt). Complexes 2a-c could also react with silyl halides to afford diazene complexes [(ICy)2Co(η2-R3SiNNSiR3)] (R = Me, 6a; Et, 6b) that are the first diazene complexes of late transition metals prepared from N2 functionalization. Characterization data, in combination with calculation results, suggest the electronic structures of the diazene complexes as low-spin cobalt(II) complexes containing dianionic ligand [η2-R3SiNNSiR3]2-. Complexes 1, 2a-c, 6a, 6b, and (ICy)2CoCl2 proved to be effective catalysts for the reductive silylation of N2 to afford N(SiMe3)3. These NHC-cobalt catalysts display comparable turnover numbers (ca. 120) that exceed the reported 3d metal catalysts. The fine performance of the NHC-cobalt complexes in the stoichiometric and catalytic N2-functionalization reactions points out the utility of low-valent low-coordinate group 9 metal species for N2 fixation.

New complexes of 4-[(4-fluorophenyl)amino]-4-oxobut-2-enoic acid with selected transition metal ions: Synthesis, thermal, and magnetic properties

Complexes of 4-[(4-fluorophenyl)amino]-4-oxobut-2-enoic acid, HL, with Mn(II), Co(II), Ni(II), Cu(II), Nd(III), Gd(III), and Er(III) were synthesized and characterized by various physico-chemical methods: elemental analysis, FT-IR, TG, DTG, DSC, TG/FT-IR, XRF, XRD, and magnetic measurements using the Gouy’s method and a SQUID-VSM magnetometer. The complexes were found to be hydrates (except Er(III) complex) containing 1 to 4 molecules of water. The carboxylate groups acted as bidentate ligands.

Enantioselective precipitate of amines, amino alcohols, and amino acids via schiff base reaction in the presence of chiral ionic liquid

Two novel chiral ionic liquids are synthesized as the chiral selector. Racemates of amines, amino alcohols, and amino acids could generate enantioselective precipitate with multicomponent self-assemblies under mild conditions. The approach allows for enan

Synthesis and Characterization of 2-Pyridinylmethylene-2-quinolyl Hydrazone Cobalt(III) Complexes. Reactivity Trends and Solvent Effect on the Initial and Transition States of Base Catalyzed Hydrolysis

The complexes of pyridine-2-aldehyde-2-quinolylhydrazone Co(III) nitrate [Co(paqh)2](NO3)2, methyl-2-pyridylketone-2-quinolinhyrazone Co(III) nitrate [Co(mpkqh)2](NO3)2, and phenyl-2-pyridylketon-2-quinolinhyrazone Co(III) nitrate [Co(ppkqh)2](NO3)2 were prepared and characterized. Solubilities of Co(III)–hydrazone complexes were measured. Transfer chemical potentials were calculated from the measured solubilities of the Co(III) complexes in aqueous methanol mixtures at 25?°C. The reactivity trends in the transfer chemical potentials are discussed in terms of the nature of the bonded ligands. Kinetics of the base hydrolysis of Co(III)–hydrazone complexes in the aqueous methanol mixtures have been studied at 25?°C, and follow the rate law kobs?=?k2[OH?]. The solvent effects on the reactivity trends of Co(III) complexes are analyzed into initial state (is) and transition states (ts) components. The reaction rates are reduced by the increase of methanol content. The destabilization of the transition state is remarkable compared to the initial state in the aqueous methanol mixtures. The initial state is more hydrophobic in nature than the transition state for Co(III) complex reactions.

N-Atom transfer: Via thermal or photolytic activation of a Co-azido complex with a PNP pincer ligand

Thermal or photolytic activation of well-defined mononuclear [Co(N3)(PNP)] (PNP = 2,2′-bis(diisopropylphosphino)-4,4′-ditolylamido) results in the structurally characterized dinuclear species [Co(μ-N;κ3-P,N,N-PNPN)]2 (3), with two N-bridging phosphiniminato bridgeheads. Density Functional Theory (DFT) calculations indicate the intermediacy of a mononuclear cobalt-nitrido complex, followed by N-migratory insertion into a Co-P bond. Reaction of 3 with two equiv. HCl leads to rupture of the dimer with formation of mononuclear [CoCl(PNPNH)] (4) by protonation of the N-bridges.

Synthesis and molecular structure of cobalt(II) complex with 1-(1-silatranylmethyl)-1,2,4-triazole

Reaction of cobalt chloride with 1-(1-silatranylmethyl)-1,2,4-triazole in benzene afforded complex CoCl2·2L (L = 1-(1-silatranylmethyl)- 1,2,4-triazole). It was isolated as the solvate [CoCl2·2L] ·CH2Cl2 (1) by recrystallization from dichloromethane and structurally characterized by single-crystal X-ray diffraction. It crystallizes in the monoclinic space group P21/m with a = 6.798(2) E, b = 20.326(5) E, c = 11.005(3) E, and Z = 4. The cobalt atom is in slightly distorted square-planar environment, coordinated to two nitrogen atoms from two ligands and two chloride ions.

Microwave-assisted carbohydrohalogenation of first-row transition-metal oxides (M = V, Cr, Mn, Fe, Co, Ni, Cu) with the formation of element halides

The anhydrous forms of first-row transition-metal chlorides and bromides ranging from vanadium to copper were synthesized in a one-step reaction using the relatively inexpensive element oxides, carbon sources, and halogen halides as starting materials. The reactions were carried out in a microwave oven to give quantitative yields within short reaction times.