17269-94-2

Basic information

• Product Name: p-tert-butylphenetole
• Synonyms: 1-Ethoxy-4-tert-butylbenzene;4-tert-Butyl-1-ethoxybenzene;4-(TERT-BUTYL)-PHENETOLE;p-tert-butylphenetole
• CAS NO: 17269-94-2
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 178.27072
• EINECS: 241-305-0
• Mol File: 17269-94-2.mol

Chemical Properties

• Boiling Point: 240°Cat760mmHg
• Flash Point: 101.2°C
• Appearance: /
• Density: 0.906g/cm³
• Vapor Pressure: 0.0601mmHg at 25°C
• Refractive Index: 1.48
• CAS DataBase Reference: p-tert-butylphenetole(CAS DataBase Reference)
• NIST Chemistry Reference: p-tert-butylphenetole(17269-94-2)
• EPA Substance Registry System: p-tert-butylphenetole(17269-94-2)

Safety Data

• Hazardous Substances Data: 17269-94-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H18O/c1-5-13-11-8-6-10(7-9-11)12(2,3)4/h6-9H,5H2,1-4H3

Upstream product

• 78-83-1 2-methyl-propan-1-ol 
• 7664-93-9 sulfuric acid 
• 103-73-1 Phenetole 
• 75-65-0 tert-butyl alcohol 
• 383-63-1 ethyl trifluoroacetate, 
• 98-54-4 para-tert-butylphenol 
• 1569262-64-1 ethyl N-tert-butyl-4-nitrobenzenesulfonimidate 
• 507-20-0 tertiary butyl chloride 
• 75-03-6 ethyl iodide 

Downstream Products

• 1104267-57-3 1-((5-tert-butyl-2-ethoxyphenyl)(phenyl)methyl)pyrrolidine-2,5-dione 
• 459-26-7 4-ethoxy-1-fluorobenzene 
• 81578-41-8 2-acetylamino-4-t-butyl-6-nitrophenols 
• 81578-39-4 1-ethoxy-4-t-butyl-2,6-dinitrobenzene 

Relevant articles and documents

Microwave-assisted synthesis method for ethylation reaction

The invention relates to a microwave-assisted synthesis method for an ethylation reaction. The method is characterized in that a reaction substrate is in an organic solvent, trifluoroacetic acid ethyl ester is taken as an ethylation reagent, in the presence of an alkali, microwave-assisted heating is carried out for 2 minutes, and a corresponding ethylation product can be obtained. The invention provides a new method for the ethylation reaction. The reaction rate of the method is several times higher than that of a traditional method, the operation is simple and convenient, the cost is low, the reaction time is short, the application range of the substrate is wide, the use of the expensive or hypertoxic ethylation reagent can also be avoided, and the method has higher application value.

SNAAP sulfonimidate alkylating agent for acids, alcohols, and phenols 1

Stable, crystalline ethyl N-tert-butyl-4-nitrobenzenesulfonimidate has been prepared in high yield by direct O-ethylation of N-tert-butyl-4- nitrobenzenesulfonamide with iodoethane and silver(I) oxide in dichloromethane. This sulfonimidate directly ethylates various acids to esters; the stronger the acid, the faster it alkylates and in higher yield. It readily ethylates alcohols and phenols to ethers at room temperature in the presence of tetrafluoroboric acid catalyst without molecular rearrangements or racemization. We have defined these reactions as SNAAP alkylations: [substitution, nucleophilic of acids, alcohols and phenols]. The hard sulfonimidate alkylating agent is chemoselective, preferring oxygen > nitrogen > sulfur. The sulfonamide byproduct of alkylation is readily recycled to the sulfonimidate. Georg Thieme Verlag Stuttgart . New York.

Rhenium complexes-catalyzed alkylation of arenes with alkyl halides

Rhenium complexes have been shown to catalyze the alkylation of arenes with alkyl halides. When arenes were reacted with an alkyl chloride in the presence of a catalytic amount of rhenium complexes, such as bromopentacarbonylrhenium(I) [ReBr(CO)5], tricarbonylcyclopentadienylrhenium(I) [Re(C5H5)(CO)3] and decacarbonyldirhenium [Re2(CO)10], alkylation of the arenes proceeded under mild conditions to give a mixture of mono- and dialkyl substituted arenes in moderate-to-good yields.