19920-08-2Relevant articles and documents
COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME
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Paragraph 0235-0238; 0383-0386, (2021/02/02)
The present specification relates to a compound represented by chemical formula 1 and an organic light emitting device including the same. When the compound is used in an organic material layer of the organic light emitting device, lifespan characteristics thereof can be improved.
Highly Enantioselective Cobalt-Catalyzed Hydroboration of Diaryl Ketones
Liu, Wenbo,Guo, Jun,Xing, Shipei,Lu, Zhan
, p. 2532 - 2536 (2020/04/02)
A highly enantioselective cobalt-catalyzed hydroboration of diaryl ketones with pinacolborane was developed using chiral imidazole iminopyridine as a ligand to access chiral benzhydrols in good to excellent yields and ee. This protocol could be carried out in a gram scale under mild reaction conditions with good functional group tolerance. Chiral biologically active 3-substituted phthalide and (S)-neobenodine could be easily constructed through asymmetric hydroboration as a key step.
Palladium-Catalyzed Ligand-Free Decarboxylative Coupling of α- Oxocarboxylic Acid with Aryl Diazonium Tetrafluoroborate: An Access to Unsymmetrical Diaryl Ketones
Panja, Subir,Maity, Pintu,Ranu, Brindaban C.
, p. 12609 - 12618 (2018/10/20)
Diaryl ketones are of much importance in organic synthesis as versatile intermediates and in industry for their useful properties. A mild and efficient palladium-catalyzed traditional ligand-free decarboxylative coupling of aryl α-keto carboxylic acid with aryl diazonium fluoroborate has been developed. A series of unsymmetrical diaryl ketones has been synthesized in moderate to good yields using this procedure. A radical pathway involving the acyl radical has been suggested.
Cobalt-Catalyzed Asymmetric Hydrogenation of 1,1-Diarylethenes
Chen, Jianhui,Chen, Chenhui,Ji, Chonglei,Lu, Zhan
supporting information, p. 1594 - 1597 (2016/05/02)
Highly enantioselective cobalt-catalyzed hydrogenation of 1,1-diarylethenes was developed by using bench-stable chiral oxazoline iminopyridine-cobalt complexes as precatalysts. A unique o-chloride effect was observed to achieve high enantioselectivity. Easy removal as well as further transformations of the chloro group make this protocol a potentially useful alternative to synthesize various chiral 1,1-diarylethanes. This process can be successfully performed under 1 atm of hydrogen at room temperature on gram scale.
IMPROVED MANUFACTURING PROCEDURE FOR THE PREPARATION OF POLYMORPHIC FORM II OF CIS-(1S)-N-METHYL-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPTHLENEAMINE HYDROCHLORIDE (SERTRALINE HYDROCHLORIDE)
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Page/Page column 20, (2008/06/13)
The present invention relates to the improved, scalable and efficient manufacturing procedure for the preparation of the antidepressant Cis-(1S)-N-Methyl-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-napthaleneamine hydro chloride, Sertraline Hydrochloride polymorphic form II. The present invention further relates to the improved and modified procedures for preparing, separating and isolating the key intermediates involved in the preparationof Sertraline Hydrochloride polymorphic form II. The present invention also further relates to the use of novel reagents or a combination thereof and new methodologies to prepare some o'f the key intermediates involved in the preparation of Polymorphic Form II of Sertraline Hydrochloride.
Gallium nonafluorobutanesulfonate as an efficient catalyst in Friedel- Crafts acylation
Matsuo, Jun-Ichi,Odashima, Kazunori,Kobayashi, Shu
, p. 403 - 405 (2007/10/03)
Catalytic Friedel-Crafts acylation of even inactivated benzenes has been successfully carded out using a gallium compound. In the presence of a catalytic amount of gallium nonafluorobutanesulfonate (1-5 mol%), aromatics including inactivated benzenes such as fluorobenzene, chlorobenzene, and dichlorobenzene reacted with carboxylic acid chlorides or anhydrides to afford the corresponding aromatic ketones in good to excellent yields. Contrary to traditional understandings, catalytic Friedel-Crafts acylation was successfully carried out using the group 13 compound.