27490-32-0

Basic information

• Product Name: Stannane, tributyl(methoxymethyl)-
• CAS NO: 27490-32-0
• Molecular Formula: C14H32OSn
• Molecular Weight: 335.117
• Mol File: 27490-32-0.mol

Chemical Properties

• CAS DataBase Reference: Stannane, tributyl(methoxymethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Stannane, tributyl(methoxymethyl)-(27490-32-0)
• EPA Substance Registry System: Stannane, tributyl(methoxymethyl)-(27490-32-0)

Safety Data

• Hazardous Substances Data: 27490-32-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Stannane, tributyl(methoxymethyl)is employed as a nucleophilic reducing agent for the selective reduction of carbonyl compounds, which is crucial in the synthesis of various organic molecules. Its ability to selectively reduce specific functional groups without affecting others makes it a valuable tool in organic chemistry.
Used in Radical Reactions:
In the field of radical chemistry, Stannane, tributyl(methoxymethyl)serves as a source of tributylstannyl radicals, which are essential in initiating and propagating radical reactions. This application is vital for the synthesis of complex organic molecules that require radical intermediates.
Used in Laboratory Settings:
Stannane, tributyl(methoxymethyl)is a widely used reagent in laboratory settings, where its unique properties are harnessed for the preparation of a variety of organic compounds. Its versatility and reactivity make it an indispensable tool for chemists working in the field of organic synthesis.
Used in the Preparation of Organic Compounds:
Stannane, tributyl(methoxymethyl)is also known for its use in the preparation of various organic compounds, where its reactivity and selectivity are leveraged to synthesize target molecules with high yields and purity. This application underscores its importance in the development of new chemical entities and pharmaceuticals.

Upstream product

• 107-30-2 chloromethyl methyl ether 
• 865-47-4 potassium tert-butylate 
• 66222-29-5 tri-n-butylstannylmethyl iodide 
• 79411-61-3 chloromethoxymethyltributyltin 
• 688-73-3 tri-n-butyl-tin hydride 
• 4226-01-1 tributylstannyllithium 
• 27262-82-4 tributylstannylmagnesium chloride 

Downstream Products

• 1195-44-4 4-chlorobenzyl methyl ether 
• 538-86-3 benzyl methyl ether 
• 1515-81-7 1-methoxy-4-(methoxymethyl)benzene 
• 104681-81-4 1-Methoxymethyl-cyclohex-2-enol 
• 104681-82-5 3-Methoxymethyl-cyclohexanone 
• 59579-08-7 2-methoxymethylchlorobenzene 
• 21998-86-7 1-methoxy-2-methoxymethylbenzene 
• 7116-51-0 α-methoxy-m-xylene 
• 3395-88-8 4-methylbenzyl methyl ether 
• 15018-12-9 2-methoxymethyltoluene 
• 104681-83-6 1-Methoxy-3-phenyl-butan-2-ol 
• 104681-83-6 1-Methoxy-3-phenyl-butan-2-ol 
• 1515-85-1 4-(methoxymethyl)benzonitrile 
• 123266-36-4 benzhydryl (7S,6R)-7-(phenoxyacetamido)-3-(methoxymethyl)-1-carba-1-dethia-3-cephem-4-carboxylate 

Relevant articles and documents

SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING

A compound of formula (I), wherein: R1 is selected from (i) H, (ii) C3-6cycloalkyl, (iii) C3-7heterocyclyl optionally substituted with a group selected from: methyl and ester, and (iv) linear or branched C1-4alkyl optionally substituted with a group selected from: alkoxy, amino, amido, acylamido, acyloxy, alkyl carboxyl ester, alkyl carbamoyl, alkyl carbamoyl ester, phenyl, phosphonate ester, C3-7heterocyclyl optionally substituted with a group selected from methyl and oxo, and a naturally occurring amino acid, optionally N-substituted with a group selected from methyl, acetyl and boc; A1 is CRA or N; A2 is CRB or N; A3 is CRC or N; A4 is CRD or N; where no more than two of A1, A2, A3, and A4 may be N; one or two of RA, RB, RC, and RD, (if present) are selected from H, F, Cl, Br, Me, CF3, cyclopropyl, cyano, OMe, OEt, CH2OH, CH2OMe and CH2NMe2; the remainder of RA, RB, RC, and RD, (if present) are H; Y is O, NH or CH2; RY is selected from: (RYA) and (RYB).

TYK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

TYK2 INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

ALKYLAMINOPYRIDINE DERIVATIVE

The present invention relates to a compound that is useful for treatment of, for example, hypertension, arteriosclerosis, bulimia and obesity because of having an antagonistic action to a neuropeptide Y receptor and is represented by formula (I) [wherein R1 represents hydrogen, cyano, or the like; R represents a group represented by formula (II); X1 represents C1-4 lower alkylene or the like; X2 represents lower alkylene or the like; and Het represents a 5-membered heteroaromatic ring that has at least one nitrogen atom and, in addition, one or two hetero atoms selected from the group consisting of nitrogen, sulfur and oxygen atoms] or to a pharmaceutically acceptable salt thereof.

PYRIDINE DERIVATIVES SUBSTITUTED BY HETEROCYCLIC RING AND PHOSPHONOAMINO GROUP, AND ANTI-FUNGAL AGENT CONTAINING SAME

Anti-fungal agent having excellent anti-fungal action physicochemical properties including safety and water solubility. Compound represented by formula (I), or salt thereof: wherein R1 represents hydrogen, halogen, amino, R11-NH- wherein R11 represents C1-6 alkyl, hydroxy C1-6 alkyl, C1-6 alkoxy C1-6 alkyl, or C1-6alkoxycarbonyl C1-6 alkyl, R12-(CO)-NH- wherein R12 represents C1-6 alkyl group or C1-6 alkoxy C1-6 alkyl, C1-6 alkyl, hydroxy C1-6 alkyl, cyano C1-6 alkyl, C1-6 alkoxy, or C1-6 alkoxy C1-6 alkyl or a phosphonoamino group; R2 represents hydrogen, C1-6 alkyl, amino, or a di C1-6 alkylamino group or a phosphonoamino group; one of X and Y is nitrogen while the other is nitrogen or oxygen; ring A represents a 5- or 6-member heteroaryl ring or a benzene ring which may have a halogen atom or 1 or 2 C1-6 alkyl groups; Z represents a single bond, a methylene group, an ethylene group, oxygen, sulfur, -CH2O-, -OCH2-, -NH-, -CH2NH-, -NHCH2-, -CH2S-, or -SCH2-; R3 represents hydrogen or halogen or C1-6 alkyl, C3-8 cycloalkyl, C6-10 aryl, a 5- or 6-member heteroaryl group or a 5- or 6-member nonaromatic heterocyclic group which may have 1 or 2 substituents; and R4 represents hydrogen or halogen; provided that either R1 or R2 represents a phosphonoamino group.

PYRIDINE DERIVATIVE SUBSTITUTED BY HETEROARYL RING, AND ANTIFUNGAL AGENT COMPRISING THE SAME

The present invention provides an antifungal agent that has excellent antifungal action, and is also excellent in terms of its properties, safety, and metabolic stability. The present invention discloses a compound represented by the following formula I or a salt thereof, and an antifungal agent comprising the compound or the salt: wherein R1 represents a hydrogen atom, a halogen atom, an amino group, a C1-6 alkyl group, a C1-6 alkoxy group, or a C1-6-alkoxy-C1-6-alkyl group; R2 represents a hydrogen atom or an amino group; X, Y, Z, and W independently represent a nitrogen atom, an oxygen atom, a sulfur atom, or -CH-, provided that at least two among X, Y, and W are nitrogen atoms; the ring A represents a 5- or 6-membered heteroaryl ring or a benzene ring; Q represents a methylene group, an oxygen atom, -CH2O-, -OCH2-, -NH-, -NHCH2-, or -CH2NH-; and R3 represents a C1-6 alkyl group, a C3-8 cycloalkyl group, a C6-10 aryl group, or a 5- or 6-membered heteroaryl group, each of which may have one or two substituents.

Heterocycles substituted pyridine derivatives and antifungal agent containing thereof

An object of the present invention is to provide an antifungal agent which has excellent antifungal effects and is superior in terms of its physical properties, safety and metabolic stability. According to the present invention, there is disclosed a compound represented by the following formula (I), or a salt thereof: wherein R1 represents a hydrogen atom, a halogen atom, an amino group, a C1-6 alkyl group, a C1-6 alkoxy group or a C1-6 alkoxy C1-6 alkyl group; R2 represents a hydrogen atom, a C1-6 alkyl group, an amino group or a di C1-6 alkylamino group; one of X and Y is a nitrogen atom while the other is a nitrogen atom or an oxygen atom; ring A represents a 5- or 6-member heteroaryl ring or a benzene ring which may have a halogen atom, or 1 or 2 C1-6 alkyl groups; Z represents a single bond, a methylene group, an ethylene group, an oxygen atom, a sulfur atom, —CH2O—, —OCH2—, —NH—, —CH2NH—, —NHCH2—, —CH2S—, or —SCH2—; R3 represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, a C3-8 cycloalkyl group, a C6-10 aryl group, a 5- or 6-member heteroaryl group, or 5- or 6-member non-aromatic heterocyclic group which may have 1 or 2 substituents; and R4 represents a hydrogen atom or a halogen atom.

HYDROXYMETHYLBORON COMPOUNDS

The present invention provides compounds which are useful as safe substitutes for the organotin reagent used in coupling reaction for the oxymethylation of aromatic rings, such as alkoxymethylation or hydroxymethylation, with a palladium catalyst and which can dispense with chromatographic purification with silica gel in the production and are suitable for mass production; and compounds applicable even to the oxymethylation of aromatic ring substrates which do not permit coupling reaction by conventional technique or have low reactivity.

NOVEL ANTIMALARIA AGENT CONTAINING HETEROCYCLIC COMPOUND

Disclosed is an antimalarial agent containing a compound represented by the formula: [wherein A1 represents a 3-pyridyl group that may have a substituent, a 6-quinolyl group that may have a substituent, or the like; X1 represents a group represented by the formula -C(=O)-NH- or the like; E represents a furyl group, a thienyl group or a phenyl group; with the proviso that A1 may have one to three substituents, and E has one of two substituents] or a salt thereof or hydrates thereof.

ANTIFUNGAL AGENT CONTAINING PYRIDINE DERIVATIVE

The present invention provides an antifungal agent that has superior antifungal action and is also superior in terms of physical properties, safety and metabolic stability. The present invention discloses a compound represented by the formula (I): (wherein X represents an oxygen atom, a sulfur atom or -NH-, R1 represents a hydrogen atom, a halogen atom, a cyano group, an amino group or a substituent, and R2 and R3 independently represent a hydrogen atom, a halogen atom, a hydroxyl group or a substituent, except for a case in which R2 and R3 are both hydrogen atoms), and an antifungal agent containing the above compound.