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2-[(4-chlorophenyl)amino]-1,2-diphenylethanone is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • (3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclo

    Cas No: 58268-09-0

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  • 58268-09-0 Structure
  • Basic information

    1. Product Name: 2-[(4-chlorophenyl)amino]-1,2-diphenylethanone
    2. Synonyms: Acetophenone, 2-phenyl-2-(4-chlorophenylamino)
    3. CAS NO:58268-09-0
    4. Molecular Formula: C20H16ClNO
    5. Molecular Weight: 321.8001
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 58268-09-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 511.5°C at 760 mmHg
    3. Flash Point: 263.1°C
    4. Appearance: N/A
    5. Density: 1.246g/cm3
    6. Vapor Pressure: 1.41E-10mmHg at 25°C
    7. Refractive Index: 1.655
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-[(4-chlorophenyl)amino]-1,2-diphenylethanone(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-[(4-chlorophenyl)amino]-1,2-diphenylethanone(58268-09-0)
    12. EPA Substance Registry System: 2-[(4-chlorophenyl)amino]-1,2-diphenylethanone(58268-09-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 58268-09-0(Hazardous Substances Data)

58268-09-0 Usage

General Description

2-[(4-chlorophenyl)amino]-1,2-diphenylethanone, also known as diclofenac, is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used for its analgesic and anti-inflammatory properties. It works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain and inflammation. Diclofenac is often prescribed for the treatment of conditions such as arthritis, muscle pain, and menstrual cramps. It can be taken orally in the form of a pill, or applied topically in the form of a gel or patch. However, diclofenac can have side effects such as stomach ulcers, gastrointestinal bleeding, and an increased risk of heart attack and stroke, so it is important to use this medication under the guidance of a healthcare professional.

Check Digit Verification of cas no

The CAS Registry Mumber 58268-09-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,2,6 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 58268-09:
(7*5)+(6*8)+(5*2)+(4*6)+(3*8)+(2*0)+(1*9)=150
150 % 10 = 0
So 58268-09-0 is a valid CAS Registry Number.

58268-09-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:58268-09-0 SDS

58268-09-0Relevant articles and documents

Metal-free greener method for the synthesis of densely functionalized pyrroles via a one-pot three-component reaction

Fatahpour, Maryam,Hazeri, Nourallah,Maghsoodlou, Malek Taher,Lashkari, Mojtaba

, p. 111 - 116 (2019)

Abstract: A convenient and straightforward acid-promoted synthesis of a new series of polyfunctionalized pyrroles has been developed based on a one-pot three-component reaction of acetoacetanilide, benzoin, and ammonium acetate/diverse anilines in acetic

Palladium-catalyzed oxidative cross-coupling for the synthesis of α-amino ketones

Wei, Xiao-Hong,Li, Zhen-Hua,Zhao, Lian-Biao,Zhang, Ping,Zhou, Han-Cheng,Wang, Yan-Bin

, p. 32081 - 32084 (2019)

A novel oxidative cross-coupling reaction for the synthesis of α-aryl α-amino ketones in the presence of palladium catalysts using T+BF4- as an oxidant has been developed. This transformation was achieved by direct C-H oxi

Catalyst-free facile and efficient one-pot synthesis of densely functionalized pyrroles and α-amino ketones

Vanga, Sivarama Krishna Reddy,Bollikolla, Hari Babu,Peruri, V. V. Satyanarayana

supporting information, p. 892 - 899 (2021/02/01)

An efficient catalyst-free one-pot three-component synthesis of penta-substituted pyrroles has been successfully developed. A variety of penta-substituted pyrroles were straightforwardly synthesized from good to excellent yields (78%–93%) by using easily

Preparation method of alpha-aryl alpha-aminoketone compounds

-

Paragraph 0038-0039, (2020/01/25)

The invention discloses a preparation method of alpha-aryl alpha-aminoketone compounds. The method comprises the following steps: 1) putting an alpha-aminocarbonyl compound, arylboronic acid, a catalyst and an oxidant into a reaction container, introducin

Synthesis and lung cancer cell line study of pyrrolo[2,3-d]pyrimidine analogs

Dholakia, Sandip P.,Kanada, Kaushik B.,Sureja, Dipen K.,Patel, Jitendra S.

, p. 367 - 372 (2020/01/03)

Three series of new pyrrolo[2,3-d]pyrimidines having diverse groups at position C4 and N7 of the pyrrolo[2,3-d]pyrimidine core were synthesized and their cell line study on the National Cancer Institute (NCI) H1 299 lung cancer cell line was performed. The details of the synthetic methods and characterization data of the synthesized compounds have been presented in this study. Compounds 08a, 08h, 08j, 09h, 09i, 09j, 09m, 09n, and 09o showed excellent anticancer activity compared to standard doxorubicin half maximal inhibitory concentration value on NCI H1 299 (lung cancer cell line) which was nontoxic to normal Vero cell line.

SnCl2·2H2O-Catalyzed Solvent-Free Synthesis of α-Amino Ketones and Tetrasubstituted Pyrazines

Tamaddon, Fatemeh,Dehghani Tafti, Arefeh

, p. 2217 - 2220 (2016/10/11)

Solvent-free reaction of various anilines with α-hydroxy ketones catalyzed by SnCl2·2H2O provides α-amino ketones in excellent yields. While a similar reaction with aliphatic amines is applicable for the synthesis of substituted pyrazines, SnCl2·2H2O permits versatility in the solvent-free reaction of α-hydroxy ketones with ammonium acetate to give the corresponding substituted pyrazines in good to excellent yields.

Design, synthesis, assessment, and molecular docking of novel pyrrolopyrimidine (7-deazapurine) derivatives as non-nucleoside hepatitis C virus NS5B polymerase inhibitors

Mohamed, Mosaad S.,Sayed, Amira I.,Khedr, Mohammed A.,Soror, Sameh H.

, p. 2146 - 2157 (2016/04/20)

Hepatitis C virus (HCV) infection is highly persistent and presents an unmet medical need requiring more effective treatment options. This has spurred intensive efforts to discover novel anti-HCV agents. The RNA-dependent RNA polymerase (RdRp), NS5B of HC

Highly stereoselective synthesis of β-amino ketones via a mannich reaction catalyzed by cellulose sulfuric acid as a biodegradable, efficient, and recyclable heterogeneous catalyst

Nemati, Firouzeh,Fakhaei, Amir Soheyl,Amoozadeh, Ali,Hayeniaz, Yaser Saeidi

experimental part, p. 3695 - 3702 (2011/10/09)

The efficient use of cellulose sulfuric acid as a heterogeneous catalyst promotes three-component, one-pot Mannich reaction of various ketones, aromatic aldehydes, and aromatic amines in ethanol to make the corresponding β-amino ketones with high stereose

Thiazolium-derived N-heterocyclic carbene-catalyzed cross-coupling of aldehydes with unactivated imines

Li, Gong-Qiang,Dai, Li-Xin,You, Shu-Li

, p. 852 - 854 (2007/10/03)

Cross-coupling of aromatic aldehydes or benzoins with unactivated imines catalyzed by an N-heterocyclic carbene (NHC) affords α-amino ketones smoothly. The Royal Society of Chemistry.

2-(4-chloroanilino)- and 2-(4-methoxyanilino)-1,2-diphenylethanone

Batsanov, Andrei S.,Goeta, Andres E.,Howard, Judith A.K.,Soto, Bernardino,Au-Alvarez, Oscar

, p. o304-o306 (2007/10/03)

The title compounds, C20H16ClNO and C 21H19NO2, adopt syn orientations of the C=O and N - H bonds but, like their analogues, form no strong intermolecular hydrogen bonds.

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