62882-04-6Relevant articles and documents
Photoinduced Heterogeneous C?H Arylation by a Reusable Hybrid Copper Catalyst
Choi, Isaac,Müller, Valentin,Lole, Gaurav,K?hler, Robert,Karius, Volker,Vi?l, Wolfgang,Jooss, Christian,Ackermann, Lutz
supporting information, p. 3509 - 3514 (2020/03/03)
Heterogeneous copper catalysis enabled photoinduced C?H arylations under exceedingly mild conditions at room temperature. The versatile hybrid copper catalyst provided step-economical access to arylated heteroarenes, terpenes and alkaloid natural products with various aryl halides. The hybrid copper catalyst could be reused without significant loss of catalytic efficacy. Detailed studies in terms of TEM, HRTEM and XPS analysis of the hybrid copper catalyst, among others, supported its outstanding stability and reusability.
Warming Up to Oxazole: Noncryogenic Oxazole Metalation and Negishi Coupling Development
Calimsiz, Selcuk,Geier, Michael J.,Humphreys, Luke D.,Scott, Mark E.,Wang, Xiaotian
, p. 1776 - 1781 (2019/09/09)
This report details the development of several suitable noncryogenic metalation conditions for the synthesis of oxazole zincate. Subsequent rounds of high-throughput catalyst screening ultimately led to the identification of several suitable Pd sources th
DDQ-induced dehydrogenation of heterocycles for c-c double bond formation: Synthesis of 2-thiazoles and 2-oxazoles
Li, Xiangnan,Li, Cheng,Yin, Bing,Li, Cong,Liu, Ping,Li, Jianli,Shi, Zhen
, p. 1408 - 1411 (2013/07/26)
Strong as an Ox: 2-Thiazoles and 2-oxazoles are formed by oxidation of 2-thiazolines and 2-oxazolines without requiring substituents at the C4 and C5 positions. DDQ plays an important role as the oxidant in this transformation and metal is unnecessary. This general procedure shows good functional group tolerance and provides a wide variety of 2-thiazoles and 2-oxazoles in moderate to excellent yields.
Palladium-catalyzed desulfitative arylation of azoles with arylsulfonyl hydrazides
Yu, Xinzhang,Li, Xingwei,Wan, Boshun
, p. 7479 - 7482 (2012/10/29)
Palladium-catalyzed desulfitative and denitrogenative arylation of azoles with arylsulfonyl hydrazides has been achieved. A broad scope of azoles and arylsulfonyl hydrazides has been used to produce arylated azoles in high yields.
Nickel-catalyzed synthesis of oxazoles via C-S activation
Lee, Kyoungsoo,Counceller, Carla M.,Stambuli, James P.
supporting information; experimental part, p. 1457 - 1559 (2009/08/08)
The synthesis of 2-substituted oxazoles is achieved via nickel-catalyzed cross-coupling reaction of 2-methylthio-oxazole and various organozinc reagents. An extension of this method is demonstrated with a chemoselective, one-pot synthesis of unsymmetrical
Direct arylations on water: Synthesis of 2,5-disubstituted oxazoles balsoxin and texaline
Ohnmacht, Stephan A.,Mamone, Patrizia,Culshaw, Andrew J.,Greaney, Michael F.
, p. 1241 - 1243 (2008/12/21)
An efficient two-step palladium catalysed synthesis of 2,5-disubstituted oxazoles is reported. The Royal Society of Chemistry.
6-O-acyl ketolide antibacterials
-
, (2008/06/13)
6-O-Acyl ketolide antibacterials of the formula: wherein R1, R2, R3, R4, W, X, X′, Y, and Y′ are as described herein and in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.