7238-62-2

Basic information

• Product Name: ETHYL 2-CHLORO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE
• Synonyms: ETHYL 2-CHLORO-4-METHYLTHIAZOLE-5-CARBOXYLATE;ETHYL 2-CHLORO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE;Ethyl 2-chloro-4-methyl-1,3-thiazole-5-carboxylate 97%;2-Chloro-4-methyl-5-thiazolecarboxylic acid ethyl ester;Ethyl 2-chloro-4-methyl-1,3-thiazole-5-carboxylate ,97%;2-Chloro-4-methyl-5-ethoxycarbonylthiazole;2-Chloro-4-methylthiazole-5-carboxylic acid ethyl ester
• CAS NO: 7238-62-2
• Molecular Formula: C₇H₈ClNO₂S
• Molecular Weight: 205.66
• EINECS: 604-604-1
• Mol File: 7238-62-2.mol

Chemical Properties

• Melting Point: 46 °C
• Boiling Point: 116℃
• Flash Point: 277.9°C
• Appearance: /
• Density: 1.51g/cm³
• Vapor Pressure: 2.56E-12mmHg at 25°C
• Refractive Index: 1.656
• PKA: -0.10±0.10(Predicted)
• CAS DataBase Reference: ETHYL 2-CHLORO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-CHLORO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE(7238-62-2)
• EPA Substance Registry System: ETHYL 2-CHLORO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE(7238-62-2)

Safety Data

• Hazardous Substances Data: 7238-62-2(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis Industry:
ETHYL 2-CHLORO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE is used as a chemical intermediate for its crucial role in various organic synthesis methods. It contributes to the development of new compounds and materials, facilitating advancements in the chemical industry.
Used in Research and Development:
In the field of research and development, ETHYL 2-CHLORO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE serves as a valuable compound for exploring its properties and potential applications. Its unique structure and reactivity make it an interesting subject for scientific studies, potentially leading to new discoveries and innovations in chemistry.

InChI:InChI=1/C11H17ClN4O3/c12-6-9(17)7-15-8-13-10(16(18)19)11(15)14-4-2-1-3-5-14/h8-9,17H,1-7H2

Upstream product

• 40235-78-7 4-methyl-2-thiazolone-5-carboxylic acid ethyl ester 
• 7210-76-6 ethyl-2-amino-4-methylthiazole-5-carboxylate 
• 17309-13-6 ethyl 4-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxylate 
• 100616-27-1 2-[5-(2-hydroxy-ethyl)-4-methyl-thiazol-2-ylmercapto]-4-methyl-thiazole-5-carboxylic acid ethyl ester 
• 626-34-6 ethyl aminocrotonate 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 540-80-7 tert.-butylnitrite 
• 7732-18-5 water 
• 109-99-9 tetrahydrofuran 
• 56355-41-0 2-chloro-4,5-dimethyl-1,3-thiazole 
• 100135-25-9 2-(4,5-dimethyl-thiazol-2-ylmercapto)-4-methyl-thiazole-5-carboxylic acid ethyl ester 

Downstream Products

• 40235-78-7 4-methyl-2-thiazolone-5-carboxylic acid ethyl ester 
• 122945-79-3 3-Methyl-4-oxo-4H-1,9-dithia-3a,10-diaza-cyclopenta[b]fluorene-2-carboxylic acid ethyl ester 
• 122945-80-6 3-Methyl-4-oxo-5,6,7,8-tetrahydro-4H-1,9-dithia-3a,10-diaza-cyclopenta[b]fluorene-2-carboxylic acid ethyl ester 
• 122945-77-1 3-Methyl-5-oxo-7-phenyl-5H-thiazolo[3,2-a]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 122945-83-9 1-Methyl-10-oxo-10H-3,9-dithia-4,10a-diaza-cyclopenta[b]fluorene-2-carboxylic acid ethyl ester 
• 122945-82-8 2-(4-Chloro-phenyl)-7-methyl-9-oxo-9H-thiazolo[3,2-a]thieno[3,2-d]pyrimidine-6-carboxylic acid ethyl ester 
• 122945-81-7 7-Methyl-9-oxo-2-phenyl-9H-thiazolo[3,2-a]thieno[3,2-d]pyrimidine-6-carboxylic acid ethyl ester 
• 40003-48-3 2-chloro-4-methylthiazole-5-carboxylic acid 
• 40003-12-1 4-methyl-2-phenoxy-thiazole-5-carboxylic acid ethyl ester 
• 72850-83-0 2-(2,4-dichloro-phenoxy)-4-methyl-thiazole-5-carboxylic acid ethyl ester 
• 40003-15-4 ethyl 4-methyl-2-phenylsulfanylthiazole-5-carboxylate 
• 1215002-61-1 ethyl 3-(2-chloro-4-methylthiazol-5-yl)-3-oxopropanoate 
• 141-97-9 ethyl acetoacetate 
• 1094342-52-5 3-chloro-5-[(6-chloro-2-fluoro-3-{[5-(4-methyl-2-oxo-2,3-dihydro-1,3-thiazol-5-yl)-1,3,4-oxadiazol-2-yl]methyl}phenyl)oxy]benzonitrile 

Relevant articles and documents

AMINOPHENYLCYCLOPROPYL CARBOXYLIC ACIDS AND DERIVATIVES AS AGONISTS TO GPR40

The present invention relates generally to novel therapeutic compounds and more particularly to novel compounds, their use as GPR40 agonists, processes for their manufacture, and intermediates useful in their preparation.

3-(substituted phenyl)-5-(substituted heterocyclyl)-1,2,4-triazole compounds

3-(Substituted phenyl)-5-(substituted heterocyclyl)-1,2,4-triazole compounds are useful as insecticides and acaricides. New synthetic procedures and intermediates for preparing the compounds, pesticide compositions containing the compounds, and methods of controlling insects and mites using the compounds are also provided.

One pot synthesis of 1,2,4-triazoles

One pot synthesis of 1,2,4-triazoles uses thioimidate intermediate and 1,2-dichloroethane solvent.

Pyrazolecarboxylic acid derivatives and plant disease control agent

The present invention provides a plant disease control agent containing as active ingredient one or more compounds of the formula [1]A--COOR 1 [1]whereinR 1 represents a hydrogen atom or a C 1 -C 4 alkyl group, andA represents a group of the formula (A-1) or (A-2) STR1 R 2 represents a C 1 -C 4 alkyl group, R 3 represents a C 1 -C 4 alkyl group,R 4 represents a halogen atom or a C 1 -C 4 alkyl group, andR 5 represents a C 1 -C 4 alkyl group.Further, the compound of A-1 in the formula [1] in which R 3 is a halogen atom is also included in the present invention.

Syntheses and Reactions of 2-Halo-5-thiazolecarboxylates

A variety of 2-halo-5-thiazolecarboxylates was prepared from substituted-3-aminoacrylates and 3-ketoesters.Selective reduction of 2-chloro-5-thiazolecarboxylates 4a, 4i and 4j with sodium borohydride in ethanol provided the corresponding 2-halo-5-thiazolemethanols 27 - 29.Nucleophilic displacement on methyl methanesulfonate (32c) occured selectivity at the 5-substituent to provide 2-chloro-4-(trifluoromethyl)-5-(heteroatom-substituted methyl)thiazoles 32d-f.