88301-40-0

Basic information

• Product Name: 2-Acetamido-4-bromoanisole
• Synonyms: 2-Acetamido-4-bromoanisole;N-(5-Bromo-2-methoxyphenyl)acetamide
• CAS NO: 88301-40-0
• Molecular Formula: C₉H₁₀BrNO₂
• Molecular Weight: 244.0852
• Mol File: 88301-40-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Acetamido-4-bromoanisole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Acetamido-4-bromoanisole(88301-40-0)
• EPA Substance Registry System: 2-Acetamido-4-bromoanisole(88301-40-0)

Safety Data

• Hazardous Substances Data: 88301-40-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
2-Acetamido-4-bromoanisole is used as a building block for the synthesis of pharmaceuticals and other bioactive molecules. Its unique chemical properties make it a valuable component in the development of new drugs and therapeutic agents.
Used in Organic Synthesis:
2-Acetamido-4-bromoanisole is used as a key intermediate in the synthesis of various organic compounds. Its versatility in chemical reactions allows for the creation of a wide range of molecules with different functional groups and properties.
Used in Research and Development:
2-Acetamido-4-bromoanisole is of interest to researchers and industries for its potential biological activities and applications. Its unique structure and properties make it a promising candidate for further study and development in various scientific and industrial fields.

Upstream product

• 93-26-5 2-methoxyacetanilide 
• 33696-00-3 4-bromo-1-methoxy-2-nitrobenzene 
• 108-24-7 acetic anhydride 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 
• 107986-49-2 N-(5-bromo-2-hydroxyphenyl)acetamide 
• 74-88-4 methyl iodide 
• 40925-68-6 2-amino-4-bromo-phenol 
• 95-55-6 2-amino-phenol 
• 614-80-2 2-(acetylamino)phenol 

Downstream Products

• 6358-77-6 5-bromo-2-methoxyaniline 
• 1256360-26-5 N-[2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide 

Relevant articles and documents

Method for preparing N-(3-acetyl-2-hydroxyphenyl)acetamide

The invention relates to the technical field of organic synthesis and medicine, and provides a method for preparing N-(3-acetyl-2-hydroxyphenyl)acetamide. According to the method, 2-aminophenol is adopted as an initial raw material, amidogen acetylation and a methylation reaction of phenolic hydroxyl groups are firstly carried out, then bromination on benzene rings is carried out, acetyl is introduced, reductive debromination is finally carried out, a target product is obtained, and the total yield reaches up to 41.7%. In the process of generating a compound E through a compound D, the compound D is subjected to ether bond cracking, and can react with acetylchloride to generate phenolic ester, and then a rearrangement reaction occurs. According to the method, the raw material is wide in source and easy to obtain, the path can be industrialized easily, fewer impurities are generated, the yield is high, and the purity of the target product is effectively improved.

1,2,4-TRIAZINE-4-AMINE DERIVATIVES

According to the invention there is provided a compound of formula A1 which may be useful in the treatment of a condition or disorder ameliorated by the inhibition of the A1- A2b or, particularly, the A2a receptor wherein the compound of formula A1 has the structure, wherein, A represents Cy1 or HetA; Cy1 represents a 5- to 14-membered aromatic, fully saturated or partially unsaturated carbocyclic ring system comprising one, two or three rings, which Cy1 group is optionally substituted by one or more R4a substituents; HetA represents a 5- to 14-membered heterocyclic group that may be aromatic, fully saturated or partially unsaturated, and which contains one or more heteroatoms selected from O, S and N, which heterocyclic group may comprise one, two or three rings and which HetA group is optionally substituted by one or more R4b substituents; B represents a Cy2 or HetB; Cy2 represents a 3- to 10-membered aromatic, fully saturated or partially unsaturated carbocyclic ring system comprising one or two rings, which Cy2 group is optionally substituted by one or more R4c substituents; HetB represents a 3- to 10-membered heterocyclic group that may be aromatic, fully saturated or partially unsaturated, and which contains one or more heteroatoms selected from O, S and N, which heterocyclic group may comprise one or two rings and which HetB group is optionally substituted by one or more R4d substituents.