937-54-2Relevant articles and documents
Preparation and application of 5-bromoquinazoline derivative
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Paragraph 0032-0034, (2021/02/16)
The invention discloses a 5-bromoquinazoline derivative shown in the corresponding formula. A synthesis method of the 5-bromoquinazoline derivative compound (I) comprises the following steps: weighing1.18 g of 5-bromoisatin, 2.5503g of ammonium formate an
METAL-IODIDE CATALYTIC SYSTEM FOR DIRECT ETHERIFICATION FROM ALDEHYDES AND/OR KETONES
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Page/Page column 13; 14, (2020/01/24)
A process for etherification of aldehydes and/or ketones in the presence of a catalyst and an iodine source.
Reductive Etherification of Aldehydes and Ketones with Alcohols and Triethylsilane Catalysed by Yb(OTf)3: an Efficient One-Pot Benzylation of Alcohols
Pelosi, Azzurra,Lanari, Daniela,Temperini, Andrea,Curini, Massimo,Rosati, Ornelio
supporting information, p. 4527 - 4539 (2019/08/26)
The one-pot synthesis of symmetrical and unsymmetrical ethers from aldehydes and ketones can be conveniently performed using Yb(OTf)3 as catalyst and triethylsilane as reducing agent in presence of alcohols. This methodology leads to the synthesis of ether derivatives with good yields. Notably, this process resulted a useful tool to protect alcohols as benzyl ether derivatives using differently substituted benzaldehydes as protecting agents under mild conditions. A plausible mechanism was also proposed. (Figure presented.).
Synthesis of Benzyl Alkyl Ethers by Intermolecular Dehydration of Benzyl Alcohol with Aliphatic Alcohols under the Effect of Copper Containing Catalysts
Bayguzina,Gimaletdinova,Khusnutdinov
, p. 1148 - 1155 (2018/10/24)
Synthesis of benzyl alkyl ethers was performed in high yields by intermolecular dehydration of benzyl and primary, secondary, tertiary alcohols under the effect of copper containing catalysts. The formation of benzyl alkyl ethers occurs with participation of benzyl cation.
Palladium on Carbon-Catalyzed Benzylic Methoxylation for Synthesis of Mixed Acetals and Orthoesters
Yasukawa, Naoki,Kanie, Takafumi,Kuwata, Marina,Monguchi, Yasunari,Sajiki, Hironao,Sawama, Yoshinari
supporting information, p. 10974 - 10977 (2017/08/22)
The palladium on carbon (Pd/C)-catalyzed direct methoxylation of the benzylic positions of linear benzyl and cyclic ether substrates proceeded in the presence of i-Pr2NEt under an oxygen atmosphere to give the corresponding mixed acetals. Cyclic acetal derivatives could also be converted into orthoesters. The present direct methoxylation via a carbon-hydrogen (C?H) functionalization can be accomplished using the easily-removed Pd/C and molecular oxygen as a green oxidant. The obtained mixed acetals were transformed into the corresponding ether products by chemoselective substitution of the methoxy group using a silyltriflate, 2,4,6-collidine, and a nucleophile. The orthoester derivative could also be transformed into the cyclic ketal under similar reaction conditions.
Auto-Tandem Catalysis with Frustrated Lewis Pairs for Reductive Etherification of Aldehydes and Ketones
Bakos, Mária,Gy?m?re, ádám,Domján, Attila,Soós, Tibor
supporting information, p. 5217 - 5221 (2017/04/27)
Herein we report that a single frustrated Lewis pair (FLP) catalyst can promote the reductive etherification of aldehydes and ketones. The reaction does not require an exogenous acid catalyst, but the combined action of FLP on H2, R-OH or H2O generates the required Br?nsted acid in a reversible, “turn on” manner. The method is not only a complementary metal-free reductive etherification, but also a niche procedure for ethers that would be either synthetically inconvenient or even intractable to access by alternative synthetic protocols.
A novel method for synthesis of benzyl alkyl ethers using Vanadium-based metal complex catalysts
Khusnutdinov,Bayguzina,Gallyamova,Dzhemilev
, p. 261 - 266 (2012/10/29)
A novel method has been developed for the synthesis of benzyl alkyl ethers in 25-85% yields via the reaction of toluene with alcohols in a CCl4 medium catalyzed by Et3N-activated VO(acac)2.
New method for the synthesis of benzyl alkyl ethers mediated by FeSO 4
Joshi, Girdhar,Adimurthy, Subbarayappa
experimental part, p. 720 - 728 (2011/03/22)
The synthesis of benzyl alkyl ethers from benzyl bromides and alcohols using FeSO4 as a recoverable and reusable mediator has been described without use of base and cosolvent under mild conditions.
Triflic acid catalyzed reductive coupling reactions of carbonyl compounds with O-, S-, and N-nucleophiles
Gellert, Beate A.,Kahlcke, Nils,Feurer, Markus,Roth, Stefanie
supporting information; experimental part, p. 12203 - 12209 (2011/11/07)
Highly efficient metal-free reductive coupling reactions of aldehydes and ketones with a range of nucleophiles in the presence of triflic acid (1-5 mol %) as the catalyst are presented. The reactions can be performed at ambient temperature without exclusion of moisture or air. A range of symmetrical and unsymmetrical ethers were obtained by this method in high yields and short reaction times. For the first time, the influence of additional functionalization has been studied. Furthermore, the formation of thioethers from ketones (by addition of unmodified thiols) and of sulfonamides from either aldehydes or ketones has been achieved under catalytic conditions.
Efficient preparation of new fluorinated lithium and ammonium sulfonimides
Toulgoat, Fabien,Langlois, Bernard R.,Medebielle, Maurice,Sanchez, Jean-Yves
, p. 5613 - 5616 (2008/12/21)
(Chemical Equation Presented) An efficient preparation of new fluorinated lithium and ammonium sulfonimides, from the corresponding sulfonyl fluorides, is reported. These sulfonyl fluorides are reacted with benzylamine, then triflated. Due to the high lea
