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101251-09-6

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101251-09-6 Usage

Chemical Properties

White to light yellow crystal powde

Uses

Different sources of media describe the Uses of 101251-09-6 differently. You can refer to the following data:
1. Reactant involved in:Synthesis of TpI2 kinase inhibitorsBiological evaluation of modulators of survival motor neuron proteinCross-coupling with conjugated dienes or terminal alkenes or diazoestersSynthesis of tetrabutylammonium trifluoroboratesRhosium-catalyzed cyanation
2. 4-Acetamidophenylboronic Acid is used in the synthesis of potent chrom-4-one inhibitors of the DNA-Dependant protein kinase for use in radiotherapy and chemotherapy in cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 101251-09-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,2,5 and 1 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 101251-09:
(8*1)+(7*0)+(6*1)+(5*2)+(4*5)+(3*1)+(2*0)+(1*9)=56
56 % 10 = 6
So 101251-09-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H10BNO3/c1-6(11)10-8-4-2-7(3-5-8)9(12)13/h2-5,12-13H,1H3,(H,10,11)

101251-09-6 Well-known Company Product Price

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  • (Code)Product description
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  • Alfa Aesar

  • (H52987)  4-Acetamidobenzeneboronic acid, 96%   

  • 101251-09-6

  • 1g

  • 809.0CNY

  • Detail
  • Alfa Aesar

  • (H52987)  4-Acetamidobenzeneboronic acid, 96%   

  • 101251-09-6

  • 5g

  • 3312.0CNY

  • Detail

101251-09-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Acetamidophenylboronic acid

1.2 Other means of identification

Product number -
Other names 4-Acetylaminophenylboronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:101251-09-6 SDS

101251-09-6Relevant articles and documents

Susceptibility to hydrolysis of phenylboronic pinacol esters at physiological pH

Achilli, Cesare,Ciana, Annarita,Fagnoni, Maurizio,Balduini, Cesare,Minetti, Giampaolo

, p. 137 - 139 (2013)

Boronic acids and their esters are highly considered compounds for the design of new drugs and drug delivery devices, particularly as boron-carriers suitable for neutron capture therapy. However, these compounds are only marginally stable in water. Hydrol

A method of preparing 4-aminophenylboronic acid derivatives

-

Paragraph 0017; 0018; 0020, (2017/09/01)

The invention belongs to the technical field of medicine intermediates, and particularly relates to a method of preparing 4-aminophenylboronic acid derivatives. According to the method, 4-nitrophenylboronic acid is adopted as a raw material and subjected

Synthesis and biological activity of new 4-(Pyridin-4-yl)-(3-methoxy-5- methylphenyl)- 1H-pyrazoles derivatives as ROS Receptor tyrosine kinase inhibitors

Park, Byung Sun,El-deeb, Ibrahim M.,Yoo, Kyung Ho,Han, Dong Keun,Tae, Jin Sung,Lee, So Ha

, p. 3629 - 3634 (2013/01/16)

A series of new 4-(pyridin-4-yl)-(3-methoxy-5-methylphenyl)-1H-pyrazoles (6a-k & 7a-l) has been rationally designed based on the structure of the lead compound KIST301080, a selective ROS receptor tyrosine kinase inhibitor, in order to study the activity of ROS of this new class of inhibitors. The compounds were synthesized and screened against ROS kinase, where compound 6h showed moderate inhibitory activity with an IC50 value of 6.25 μM. The study emphasized the importance of the acetonitrile group at the pyrazole ring and also the importance of having a hydrogen bond donor on the distal phenyl ring linked to the pyridine moiety.

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