14131-84-1

Basic information

• Product Name: Diaceton-alpha-D-mannofuranose
• Synonyms: diisopropylidenemannofuranose;Diaceton-alpha-D-mannofuranose;DIACETONE-D-MANNOSE;D-Mannose diacetonide;2,3:5,6-DI-O-ISOPROPYLIDENE-A-D-MANNOFURANOSE;2,3:5,6-DI-O-ISOPROPYLIDENE-A-D-MANNOPYRANOSE;(+)-2,3:5,6-DI-O-ISOPROPYLIDENE-ALPHA-D-MANNOFURANOSE;2,3,5,6-DI-O-ISOPROPYLIDENE-ALPHA-D-MANNOFURANOSE
• CAS NO: 14131-84-1
• Molecular Formula: C₁₂H₂₀O₆
• Molecular Weight: 260.28
• EINECS: 1312995-182-4
• Product Categories: 13C & 2H Sugars;Biochemistry;O-Substituted Sugars;Sugars;aldehydes;Carbohydrates & Derivatives
• Mol File: 14131-84-1.mol

Chemical Properties

• Melting Point: 125-126 °C (dec.)(lit.)
• Boiling Point: 363.54°C (rough estimate)
• Flash Point: 171.1 °C
• Appearance: White to Off-white/Powder
• Density: 1.2377 (rough estimate)
• Vapor Pressure: 1.31E-06mmHg at 25°C
• Refractive Index: 24 ° (C=1, Acetone)
• Storage Temp.: 2-8°C
• Solubility: Acetone (Slightly, Sonicated), Chloroform (Slightly), Methanol (Slightly)
• PKA: 11.97±0.60(Predicted)
• Water Solubility: Soluble in acetone, methanol, water.
• Sensitive: Hygroscopic
• BRN: 84382
• CAS DataBase Reference: Diaceton-alpha-D-mannofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: Diaceton-alpha-D-mannofuranose(14131-84-1)
• EPA Substance Registry System: Diaceton-alpha-D-mannofuranose(14131-84-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 22-24/25-36/37-26
• WGK Germany: 3
• F: 3-21
• Hazardous Substances Data: 14131-84-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Diaceton-alpha-D-mannofuranose is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a versatile building block for the development of new drugs with potential applications in treating various diseases.
Used in Chemical Synthesis:
Diaceton-alpha-D-mannofuranose is used as a synthetic building block for the preparation of complex organic molecules. Its ability to be modified and incorporated into larger structures makes it a valuable tool in the field of organic chemistry.
Used in Research and Development:
As a research chemical, Diaceton-alpha-D-mannofuranose is used in the development of new methodologies and techniques in organic synthesis. It helps researchers understand the reactivity and properties of similar compounds, leading to the discovery of novel applications and advancements in the field.
Used in Synthesis of Ovalicin:
Diaceton-alpha-D-mannofuranose is used as a starting material in the synthesis of ovalicin, a natural product with potential biological activities. Its role in the synthesis process highlights its importance in the development of new pharmaceutical agents.
Used in Synthesis of Hikizimycin Sugar Core:
Diaceton-alpha-D-mannofuranose is also used in the synthesis of the sugar core of hikizimycin, an antibiotic with potent antibacterial properties. Its involvement in the synthesis of such an important compound underscores its utility in the pharmaceutical industry.

InChI:InChI=1/C12H20O6/c1-11(2)14-5-6(16-11)7-8-9(10(13)15-7)18-12(3,4)17-8/h6-10,13H,5H2,1-4H3/t6-,7-,8+,9+,10+/m1/s1

Upstream product

• 35023-80-4 2,3:5,6-di-O-isopropylidene-D-mannose oxime 
• 530-26-7 D-Mannose 
• 67-64-1 acetone 
• 3458-28-4 D-Mannose 
• 7306-64-1 2,3,5,6-di-O-isopropylidene-D-mannono-1,4-lactone 
• 250127-86-7 2,3:5,6-di-O-isopropylidene-1-O-(allenyl)-α-D-mannofuranoside 
• 77-76-9 2,2-dimethoxy-propane 
• 36574-21-7 α-D-mannose 
• 177562-09-3 1-O-(2-phenylacetyl)-2,3;5,6-di-O-isopropylidene-α-D-mannofuranose 
• 582-52-5 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose 
• 116-11-0 2-Methoxypropene 
• 75-52-5 nitromethane 
• 5328-37-0 L-arabinose 
• 49561-21-9 (3aR,6S,6aR)-6-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one 

Downstream Products

• 52129-03-0 2,2-dimethyl-4-phenyl-1,3-dioxolane 
• 530-26-7 D-Mannose 
• 54469-08-8 phenylmethyl 2,3:5,6-di-O-(1-methylethylidene)-α-D-mannofuranoside 
• 35880-41-2 2,3:5,6-di-O-isopropylidene-1-O-(2,4-dinitrobenzenesulfenyl)-α-D-mannofuranose 
• 57526-34-8 (+)-2,3:5,6-di-O-isopropylidene-α-D-mannofuranos-3-yl benzoate 
• 138034-65-8 (1R)-2,3-5,6-di-O-isopropylidene-1-C-phenyl-D-mannitol 
• 138034-65-8 (R)-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)((4S,5R)-5-((S)-hydroxy (phenyl)methyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methanol 
• 139535-19-6 2,3:5,6-di-O-isopropylidene-1-O-(2-nitrobenzenesulfenyl)-α-D-mannofuranose 
• 54469-11-3 Acetic acid (3aS,4S,6R,6aS)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl ester 
• 14440-57-4 1-O-acetyl-2,3:5,6-di-O-isopropylidene-α-D-mannofuranose 
• 84715-79-7 1-O-(isopropylcarbamoyl)-2,3:5,6-di-O-isopropylidene-D-mannofuranose 
• 76679-45-3 Benzyl-2,3-di-O-benzyl-5-O-(2,3:5,6-di-O-isopropyliden-β-D-mannofuranosyl)-β-D-ribofuranosid 
• 76679-42-0 Benzyl-2,3-di-O-benzyl-5-O-(2,3:5,6-di-O-isopropyliden-α-D-mannofuranosyl)-β-D-ribofuranosid 
• 93222-05-0 1,4-Anhydro-2,3-O-isopropyliden-5,6-di-O-tosyl-D-mannit 

Relevant articles and documents

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