17742-05-1

Basic information

• Product Name: 3-methoxybutan-2-one
• CAS NO: 17742-05-1
• Molecular Formula: C₅H₁₀O₂
• Molecular Weight: 102.1317
• Mol File: 17742-05-1.mol

Chemical Properties

• Boiling Point: 134.3°C at 760 mmHg
• Flash Point: 31.7°C
• Density: 0.888g/cm³
• Vapor Pressure: 8.13mmHg at 25°C
• Refractive Index: 1.385
• CAS DataBase Reference: 3-methoxybutan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methoxybutan-2-one(17742-05-1)
• EPA Substance Registry System: 3-methoxybutan-2-one(17742-05-1)

Safety Data

• Hazardous Substances Data: 17742-05-1(Hazardous Substances Data)

Upstream product

• 917-64-6 methyl magnesium iodide 
• 33695-59-9 2-methoxy-propanenitrile 
• 513-86-0 3-hydroxy-2-butanon 
• 616-38-6 carbonic acid dimethyl ester 
• 74-88-4 methyl iodide 
• 102639-94-1 2,3,7-Trimethyl-5-methoxy-1,4,5-dioxaphosphaspiro<4,4>nona-2,7-diene 
• 67-56-1 methanol 
• 18857-02-8 3-methoxybut-1-yne 
• 917-93-1 2-chloroisobutyraldehyde 
• 124-41-4 sodium methylate 
• 814-75-5 3-bromo-butanone 
• 14088-58-5 3-diazo-2-butanone 

Downstream Products

• 32778-35-1 2-dimethylaminomethyl-1-buten-3-one 
• 2861-48-5 butane-2,3-dione-bis-phenylhydrazone 
• 344871-55-2 1-diphenylphosphinoyl-3-methoxy-2-methylbutan-2-ol 
• 89358-54-3 4-diphenylphosphinoyl-2-methoxy-3-methylhexan-3-ol 
• 69930-76-3 2-diphenylphosphinoyl-4-methoxy-3-methylpentan-3-ol 

Relevant articles and documents

Isolation, structural elucidation, and absolute stereochemistry of enigmazole a, a cytotoxic phosphomacrolide from the papua new guinea marine sponge cinachyrella enigmatica

Enigmazole A (1), a novel phosphate-containing macrolide, was isolated from a Papua New Guinea collection of the marine sponge Cinachyrella enigmatica. The structure of 1, including the absolute stereochemistry at all eight chiral centers, was determined by a combination of spectroscopic analyses and a series of microscale chemical derivatization studies. Compound 1 is comprised of an 18-membered phosphomacrolide that contains an embedded exomethylene-substituted tetrahydropyran ring and an acyclic portion that spans an embedded oxazole moiety. Two additional analogues, 15-O-methylenigmazole A and 13-hydroxy-15-O-methylenigmazole A, were also isolated and assigned. The enigmazoles are the first phosphomacrolides from a marine source and 1 exhibited significant cytotoxicity in the NCI 60-cell line antitumor screen, with a mean GI50 of 1.7 μ?.

3-Methoxybutan-2-one as a sustainable bio-based alternative to chlorinated solvents

Methylation of acetoin with dimethyl carbonate was performed in a sustainable one-step process, with improved process mass intensity (PMI) and atom economy compared to previously published methods. The resulting product, 3-methoxybutan-2-one (MO) was succ

Synthesis of β-(Diphenylphosphinoyl) Ketones

The title compounds may be made by addition of phosphorus nucleophiles (Ph2PO-, Ph2POMgX, Ph2PCl) to enones, by addition of phosphorus-stabilised carbanions to a α-carbonyl cation equivalents (2,3-dichloropropene, epoxides, and α-MeO-ketones) and by oxidation of allyl diphenylphosphine oxides.