1825-64-5

Basic information

• Product Name: ISOPROPOXYTRIMETHYLSILANE
• Synonyms: ISOPROPOXYTRIMETHYLSILANE;ISOPROPYL TRIMETHYLSILYL ETHER;trimethyl-2-propoxysilane;trimethyl(1-methylethoxy)silane;(1-Methylethoxy)trimethylsilane;2-(Trimethylsilyloxy)propane;2-Propoxytrimethylsilane;trimethyl(propan-2-yloxy)silane
• CAS NO: 1825-64-5
• Molecular Formula: C₆H₁₆OSi
• Molecular Weight: 132.28
• EINECS: 217-372-7
• Mol File: 1825-64-5.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 95 °C at 760 mmHg
• Flash Point: 12 °F
• Appearance: /
• Density: 0.745 g/mL at 25 °C(lit.)
• Vapor Pressure: 52.8mmHg at 25°C
• Refractive Index: n20/D 1.378(lit.)
• CAS DataBase Reference: ISOPROPOXYTRIMETHYLSILANE(CAS DataBase Reference)
• NIST Chemistry Reference: ISOPROPOXYTRIMETHYLSILANE(1825-64-5)
• EPA Substance Registry System: ISOPROPOXYTRIMETHYLSILANE(1825-64-5)

Safety Data

• Hazard Codes: F
• Statements: 11
• Safety Statements: 16-36/37/39
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• HazardClass: 3.1
• PackingGroup: II
• Hazardous Substances Data: 1825-64-5(Hazardous Substances Data)

Usage

Definition

ChEBI: A silyl ether that is isopropanol in which the hydroxyl hydrogen is replaced by a trimethylsilyl group.

InChI:InChI=1/C6H16OSi/c1-6(2)7-8(3,4)5/h6H,1-5H3

Upstream product

• 7385-10-6 9-(trimethylsilyl)fluorene 
• 683-60-3 sodium isopropylate 
• 80431-36-3 2,2-Dimethyl-4,4-diphenyl-1,3,3-tris(trimethylsilyl)-1-aza-2-silacyclobutan 
• 67-63-0 isopropyl alcohol 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 723336-86-5 trimethylsilyl 2-methylprop-2-ene-1-sulfinate 
• 1833-53-0 2-(Trimethylsilyloxy)propene 
• 18243-21-5 trimethylsilyl formate 
• 479486-96-9 N,N-dimethyl (trimethylsilyl)methanamide 
• 7677-24-9 trimethylsilyl cyanide 
• 62521-20-4 Mo₂(O-i-Pr)6 
• 16029-98-4 trimethylsilyl iodide 
• 2857-97-8 trimethylsilyl bromide 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 38115-81-0 [di(1-methylethoxy)methyl]benzene 
• 361389-94-8 N,N-benzoyl-(2-quinoxalinyl)-4-aminobenzoic acid 
• 1001208-26-9 C₂₇H₃₄O₃ 
• 1001208-25-8 C₂₉H₃₈O₃ 
• 75-77-4 chloro-trimethyl-silane 
• 135366-83-5 aluminum dichloride isopropoxide 
• 1119301-53-9 C₂₉H₄₀O₄ 
• 1119301-51-7 C₅₃H₇₀O₆Si 
• 1614234-65-9 benzyl 4-isopropoxypiperidine-1-carboxylate 
• 1609963-13-4 (3R,3aR,6R,6aR)-3-(5-fluoro-2-nitro-phenoxy)-6-isopropoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan 
• 1349833-36-8 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl 4-(diisopropoxymethyl)phenylcarbamate 
• 98088-49-4 (3-isopropoxyhex-5-en-1-yl)benzene 
• 98088-47-2 (1-Isopropoxy-but-3-enyl)-benzene 

Relevant articles and documents

Use of silyl ethers as fluoride scavengers in RNA synthesis

Use of a fluoride ion scavenger significantly simplifies isolation of synthetic RNA.

New methods of synthesis of boron, germanium, and tin derivatives of pentavalent phosphorus thioacids

The reaction of S-trimethysilyl esters of S-propyl-4-methoxyphenyltrithiophosphonic, bis-(dialkylamido)dithiophosphoric, and S-ethyl-diethylamidotrithiophosphoric acid with trialkyl borates, triorganylbromogermanes, trimethyl(isobutylthio)germane, and tri

Novel protocol for the synthesis of organic ammonium tribromides and investigation of 1,1′-(Ethane-1,2-diyl)dipiperidinium bis(tribromide) in the silylation of alcohols and thiols

A novel and efficient protocol for the synthesis of organic ammonium tribromides (OATBs) is developed by using inexpensive and eco-friendly periodic acid as an oxidant for the conversion of Br-to Br3-. The method does not use any mineral acid and metal oxidants. The protocol is utilized to synthesize a new bis(tribromide) viz., 1,1′-(ethane-1,2-diyl)dipiperidinium bis(tribromide) (EDPBT). EDPBT is investigated as a catalyst in the silylation of alcohols and thiols by HMDS (hexamethyldisilazane) under solvent-free conditions.

Polystyrene-gallium trichloride complex: A mild, highly efficient, and recyclable polymeric lewis acid catalyst for chemoselective silylation of alcohols and phenols with hexamethyldisilazane

Polystyrene-supported gallium trichloride (PS/GaCl3) as a highly active and reusable heterogeneous Lewis acid effectively activates hexamethyldisilazane (HMDS) for the efficient silylation of alcohols and phenols at room temperature. In this he