25333-24-8

Basic information

• Product Name: METHYL 3-BENZOYLPROPIONATE
• Synonyms: TIMTEC-BB SBB008046;3-BENZOYLPROPIONIC ACID METHYL ESTER;4-OXO-4-PHENYLBUTYRIC ACID METHYL ESTER;METHYL 3-BENZOYLPROPIONATE;METHYL 4-OXO-4-PHENYLBUTYRATE;Methyl 3-benzoylpropanoate;Methyl 4-oxo-4-phenylbutanoate;Propionic acid, 3-benzoyl-, methyl ester
• CAS NO: 25333-24-8
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21
• Product Categories: Aromatic Propionic Acids
• Mol File: 25333-24-8.mol
• Article Data: 81

Chemical Properties

• Boiling Point: 172-174 °C (10 mmHg)
• Flash Point: 172-174°C/10mm
• Appearance: /
• Density: 1.14
• Vapor Pressure: 0.000707mmHg at 25°C
• Refractive Index: 1.523-1.525
• Solubility: Soluble in Chloroform.
• BRN: 2211627
• CAS DataBase Reference: METHYL 3-BENZOYLPROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-BENZOYLPROPIONATE(25333-24-8)
• EPA Substance Registry System: METHYL 3-BENZOYLPROPIONATE(25333-24-8)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 25333-24-8(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to yellow liquid

Uses

Methyl 3-benzoylpropionate is used as a chemical and organic intermediate.

InChI:InChI=1/C11H12O3/c1-14-11(13)8-7-10(12)9-5-3-2-4-6-9/h2-6H,7-8H2,1H3

Upstream product

• 41158-32-1 methyl 4-oxo-4-phenylbut-2-ynoate 
• 67-56-1 methanol 
• 2051-95-8 succinylbenzene 
• 2674-04-6 diphenyl cadmium 
• 1490-25-1 succinic acid monomethylester chloride 
• 74-85-1 ethene 
• 201230-82-2 carbon monoxide 
• 56346-03-3 C₁₁H₁₄LiNOSi 
• 22049-87-2 rac-4-nitro-4-phenyl-butyric acid methyl ester 
• 90288-93-0 2-(tert-Butyldimethylsiloxy)-2-phenyl-1-cyclopropancarbonsaeure-methylester 
• 38447-68-6 phenyl selenobenzoate 
• 292638-85-8 acrylic acid methyl ester 
• 26551-48-4 Methyl 3-bromo-4-keto-4-phenylbutanoate 
• 186581-53-3 diazomethane 

Downstream Products

• 14274-07-8 methyl 3-benzoylacrylate 
• 860361-30-4 1-phenethyl-5-phenyl-pyrrolidin-2-one 
• 103632-91-3 2-[2-(methoxycarbonyl)ethyl]-2-phenyl-1,3-dioxolane 
• 91266-20-5 (Z)-4-Methoxy-4-phenyl-but-3-enoic acid methyl ester 
• 172980-58-4 methyl 4,4-dimethoxy-4-phenylbutanoate 
• 15463-92-0 dimethyl 2-phenylsuccinate 
• 1011-46-7 6-phenyl-2,3,4,5-tetrahydropyridazin-3-one 
• 4578-59-0 2,6-diphenyl-4,5-dihydro-3(2H)-pyridazinone 
• 111138-03-5 (R)-4-phenylbutyrolactone 
• 111138-02-4 (-)-(S)-5-phenyl-4,5-dihydrofuran-2(3H)-one 
• 948018-37-9 methyl 4-[(3,5-dimethyl-4-methoxyphenyl)imino]-4-phenylbutanoate 
• 1008-76-0 4,5-dihydro-5-phenyl-2(3H)-furanone 
• 34674-93-6 4-hydroxy-4-phenylbutanoic acid 
• 1202876-41-2 C₁₅H₁₂O₄ 

Relevant articles and documents

3,6-bis(triphenylphosphonium)cyclohexene peroxodisulfate: A highly efficient oxidant for the selective oxidation of benzylic alcohols

The synthesis of 3,6-bis(triphenylphosphonium)cyclohexene peroxodisulfate and its application for the selective oxidation of benzylic alcohols is reported.

Visible-Spectrum Solar-Light-Mediated Benzylic C-H Oxygenation Using 9,10-Dibromoanthracene As an Initiator

We report a visible-light-mediated benzylic C-H oxygenation reaction. The reaction is initiated by solar light or the blue LED activation of 9,10-dibromoanthracene in a reaction with oxygen and takes place at ambient temperature and air pressure. Secondary benzylic positions are oxygenated to ketones, while tertiary benzylic carbons are oxygenated to give hydroperoxides. Notably, cumene hydroperoxide is produced in a higher yield and at milder conditions than the currently employed industrial conditions.

Photoinduced Deaminative Alkylation for the Synthesis of γ-Ketoesters via Electron Donor–Acceptor Complex Formation

Visible-light-induced deaminative alkylation of Katritzky salts with silyl enol ethers has been developed. The reaction can proceed efficiently through electron donor–acceptor complex formation, avoiding the use of precious metal complexes or synthetically elaborate organic dyes. A series of functionalized γ-ketoesters was successfully obtained with good functional group tolerance and compatibility under mild and straightforward conditions.

Tandem homologation-acylation chemistry: Single and double homologation

Treatment of β-dicarbonyls with the Furakawa-variant of the Simmons-Smith reagent results in homologation and production of an intermediate zinc enolate. Treatment of the enolate with various acylating agents generate products with both γ-dicarbonyl funct